ALEXIS Biochemicals: N-(1-Naphthalenylsulfonyl)-Ile-Trp-aldehyde

ALX-260-133

Revised 24-Feb-05

N-(1-Naphthalenylsulfonyl)-Ile-Trp-aldehyde
SYNONYMS	N-(1Naphthalenylsulfonyl)- IW-CHO
PRODUCT LINE	Cancer
PRODUCT CATEGORY	Cathepsin Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-260-133-M001		1 mg	90.00 USD
ALX-260-133-M005		5 mg	360.00 USD

Product Specification

FORMULA:	C₂₇H₂₉N₃O₄S
MW:	491.6
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Potent, selective and reversible inhibitor of human cathepsin L (IC₅₀=1.9nM). Inhibits release of Ca²⁺ and hydroxyproline from bone in vitro.

Product Specific Literature References

Synthesis of peptide aldehyde derivatives as selective inhibitors of human cathepsin L and their inhibitory effect on bone resorption: T. Yasuma, et al.; J. Med. Chem. 41, 4301 (1998) Abstract

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