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ALX-290-008 Revised 13-Jul-06
N-Acetyl-S-geranylgeranyl-L-cysteine
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SYNONYMS AGGC
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Geranyl-related Reagents
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-290-008-M005   5 mg 140.00 USD Add To Cart
Product Specification
FORMULA: C25H41NO3S
MW: 435.7
CAS NUMBER: 139332-94-8
PURITY: ≥98%
APPEARANCE: Viscous yellow oil.
SOLUBILITY: Soluble in 100% ethanol or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Specifically blocks methyl esterification of geranylgeranylated proteins such as Rab proteins. Blocks receptor-mediated signal transduction in human neutrophils (IC50=4µM). Induces insulin release from HIT-T15 cells by mimicking the action of Rab3A. Inhibits β2-integrin-induced actin polymerization (IC50~45nM) in neutrophils.
 
 

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