• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
Natural Products / Antibiotics
You are here: Product Lines > Natural Products / Antibiotics
 
Toolbar - View Selection
 
 Items 20-40 of 696 Page 2 of 35 Select Page: << 1 2 3 4 5 6 7 8 9 10  >>  
ALX-630-093 Revised 23-Jul-08
Aflatoxin B1
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-093-M001   1 mg 28.00 USD Add To Cart
ALX-630-093-M005   5 mg 110.00 USD Add To Cart
Product Specification
FORMULA: C17H12O6
MW: 312.3
CAS NUMBER: 1162-65-8
MERCK INDEX: 14: 180
RTECS: GY1925000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC)
APPEARANCE: White to yellow powder.
SOLUBILITY: Soluble in DMSO (20mg/ml) or methylene chloride (10mg/ml).
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: VERY TOXIC. MAY BE CARCINOGENIC. MAY BE TERATOGENIC.

Product Description
Naturally occuring mycotoxin produced by many species of Aspergillus. Metabolized by the liver to the reactive intermediate aflatoxin M1. Exposure may produce acute necrosis, cirrhosis and carcinoma of the liver. Induces DNA damage.
Product Specific Literature References
Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus: C.P. Wild, et al.; Environ. Health Perspect. 99, 115 (1993) Abstract
A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China: G.S. Qian, et al.; Cancer Epidemiol. Biomarkers Prev. 3, 3 (1994) Abstract
Aflatoxin B1 induced lacI mutation in liver and kidney of transgenic mice C57BL/6N: effect of phorone: H. Autrup, et al.; Mutagenesis 11, 69 (1996) Abstract
Activation and detoxication of aflatoxin B1: F.P. Guengerich, et al.; Mutat. Res. 402, 121 (1998), (Review) Abstract
Hyperplasia, partial hepatectomy, and the carcinogenicity of aflatoxin B1: B.D. Roebu; J. Cell. Biochem. 91, 242 (2004), (Review) Abstract
Aflatoxin B1-induced DNA damage and its repair: L. L. Bedard & T. E. Massey; Cancer Lett. 241, 174 (2006), (Review) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Carcinogens & Tumor Promoters Other Products • Plant Research Reagents/Related Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-103 Revised 10-Sep-07
Aflatoxin B2
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-103-M001   1 mg 55.00 USD Add To Cart
ALX-630-103-M005   5 mg 260.00 USD Add To Cart
Product Specification
FORMULA: C17H14O6
MW: 314.3
CAS NUMBER: 7220-81-7
MERCK INDEX: 14: 180
RTECS: GY1722000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in methylene chloride, DMSO or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: VERY TOXIC. MAY BE CARCINOGENIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin.
Product Specific Literature References
Aflatoxin B2: Chemical Identity and Biological Activity: S.B. Chang, et al.; Science 142, 1191 (1963) Abstract
Accumulation of only aflatoxin B2 by a strain of Aspergillus flavus: H.W. Schroeder & W.W. Carlton; Appl. Microbiol. 25, 146 (1973) Abstract
In vitro metabolism of aflatoxin B2 by animal and human liver: B.D. Roebuck, et al.; Cancer Res. 38, 999 (1978) Abstract
Interaction of aflatoxin B2 with rat liver DNA and histones in vivo: J.D. Groopman, et al.; Carcinogenesis 2, 1371 (1981) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-104 Revised 20-Mar-08
Aflatoxin G1
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-104-M001   1 mg 65.00 USD Add To Cart
ALX-630-104-M005   5 mg 260.00 USD Add To Cart
Product Specification
FORMULA: C17H12O7
MW: 328.3
CAS NUMBER: 1165-39-5
MERCK INDEX: 14: 181
RTECS: LV1720000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC)
APPEARANCE: White to yellow powder.
SOLUBILITY: Soluble in DMSO (10mg/ml), methylene chloride (5mg/ml) or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: MAY BE CARCINOGENIC. VERY TOXIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin.
Product Specific Literature References
Mutagenic effect of aflatoxin G1 in comparison with B1: M.M. el-Zawahri, et al.; J. Environ. Pathol. Toxicol. Oncol. 10, 45 (1990) Abstract
Identification of an aflatoxin G1-serum albumin adduct and its relevance to the measurement of human exposure to aflatoxins: G. Sabbioni & C.P. Wild; Carcinogenesis 12, 97 (1991) Abstract
Effects of sterigmatocystin, deoxynivalenol and aflatoxin G1 on apoptosis of human peripheral blood lymphocytes in vitro: X.M. Sun, et al.; Biomed. Environ. Sci. 15, 145 (2002) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-106 Revised 20-Jun-08
Aflatoxin G2
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-106-M001   1 mg 150.00 USD Add To Cart
ALX-630-106-M005   5 mg 600.00 USD Add To Cart
Product Specification
FORMULA: C17H14O7
MW: 330.3
CAS NUMBER: 7241-98-7
MERCK INDEX: 14: 181
RTECS: LV1700000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC)
APPEARANCE: Off-white to yellow powder.
SOLUBILITY: Soluble in methylene chloride (5mg/ml), DMSO or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: VERY TOXIC. MAY BE CARCINOGENIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin.
Product Specific Literature References
Combining Ability for Resistance to Field Aflatoxin Accumulation in Maize Grain: D.P. Gorman, et al.; Plant Breeding 109, 296 (1992)
Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential: J.J. Wong & D.P. Hsieh; PNAS 73, 2241 (1976) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-114 Revised 13-Jun-08 New product
Aflatoxin M2
Add to Clipboard
SYNONYMS 4-Hydroxyaflatoxin B2
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-114-MC01   0.1 mg 250.00 USD Add To Cart
Product Specification
FORMULA: C17H14O7
MW: 330.3
CAS NUMBER: 6885-57-0
MERCK INDEX: 14: 182
RTECS: GY1720000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥98% (HPLC, TLC)
APPEARANCE: White to light yellow powder.
SOLUBILITY: Soluble in DMSO or methanol; insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
HAZARD: VERY TOXIC. MAY BE CARCINOGENIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin. Metabolite of aflatoxin B2. DNA-damaging agent.
Product Specific Literature References
Milk of mammals fed an aflatoxin-containing diet.: H. De Iongh, et al.; Nature 202, 466 (1964) Abstract
Isolation and structure of aflatoxins M1 and M2: C.W. Holzapfel, et al.; Tetrahedron Lett. 25, 2799 (1966) Abstract
Acute toxicity of aflatoxins M1 and M2 in one-day-old ducklings: I.F. Purchase; Food Cosmet. Toxicol. 5, 339 (1967) Abstract
Occurrence of aflatoxins M(1) and M(2) in milk commercialized in Ribeirão Preto-SP, Brazil: N.S. Garrido, et al.; Food Addit. Contam. 20, 70 (2003) Abstract
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters
 
 
ALX-630-095 Revised 03-Apr-08 New product
Aflatoxin M1
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Mycotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-095-MC01   0.1 mg 80.00 USD Add To Cart
Product Specification
FORMULA: C17H12O7
MW: 328.3
CAS NUMBER: 6795-23-9
MERCK INDEX: 14: 182
RTECS: GY1880000
SOURCE/HOST: Isolated from Aspergillus flavus.
PURITY: ≥95% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in methylene chloride (1mg/ml).
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HAZARD: MAY BE MUTAGENIC. MAY BE CARCINOGENIC. VERY TOXIC.

Product Description
Potent hepatotoxic and hepatocarcinogenic mycotoxin. Hydroxylated metabolite of aflatoxin B1.
Product Specific Literature References
Production and characterization of monoclonal antibodies against aflatoxin M1: N.A. Woychik, et al.; Appl. Environ. Microbiol. 48, 1096 (1984) Abstract; Full Text
Comparative binding and sequence interaction specificities of aflatoxin B1, aflatoxicol, aflatoxin M1, and aflatoxicol M1 with purified DNA: K. Marien, et al.; J. Biol. Chem. 262, 7455 (1987) Abstract; Full Text
Presence of aflatoxin M1 in commercial ultra-high-temperature-treated milk.: J.L. Blanco, et al.; Appl. Environ. Microbiol. 54, 1622 (1988) Abstract; Full Text
Distribution and stability of aflatoxin M1 during processing, ripening and storage of Telemes cheese: A. Govaris, et al.; Food Addit. Contam. 18, 437 (2001) Abstract
General Information
Not for sale in U. S. A.
Further Categories Containing This Product:
Plant Research Reagents/Related Products • Carcinogens & Tumor Promoters Other Products • Natural Products - Plant Research Reagents • Natural Products - Other Tumor Promoters • Non-apoptotic Cell Death/Necrosis
 
 
ALX-630-001 Revised 28-May-08
ω-Agatoxin IVA
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Neurotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-001-C100   100 µg 580.00 USD Add To Cart
Product Specification
SEQUENCE: H-Lys-Lys-Lys-Cys-Ile-Ala-Lys-Asp-Tyr-Gly-Arg-Cys-Lys-Trp-Gly-Gly-Thr-Pro-Cys-Cys-Arg-Gly-Arg-Gly-Cys-Ile-Cys-Ser-Ile-Met-Gly-Thr-Asn-Cys-Glu-Cys-Lys-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Gly-Leu-Ala-OH
(Disulfide bonds between Cys4-Cys20, Cys12-Cys25, Cys19-Cys36 and Cys27-Cys34)
FORMULA: C217H360N68O60S10
MW: 5202.3
CAS NUMBER: 145017-83-0
SOURCE/HOST: Synthetic. Originally isolated from Agelenopsis aperta.
PURITY: ≥98%
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HAZARD: POTENT NEUROTOXIN.
Product Description
Selective P-type Ca2+ channel blocker.
Product Specific Literature References
P-type calcium channels blocked by the spider toxin omega-Aga-IVA: I.M. Mintz, et al.; Nature 355, 827 (1992) Abstract
Calcium channels coupled to glutamate release identified by omega-Aga- IVA: T.J. Turner, et al.; Science 258, 310 (1992) Abstract
Synthesis of omega-agatoxin IVA and its related peptides: H. Nishio, et al.; BBRC 196, 1447 (1993) Abstract
Interactions of polyamines with neuronal ion channels: R.H. Scott, et al.; TINS 16, 153 (1993), (Review) Abstract
Different types of calcium channels mediate central synaptic transmission: T. Takahashi & A. Momiyama; Nature 366, 156 (1993) Abstract
Sequential assignment and structure determination of spider toxin omega- Aga-IVB: H. Yu, et al.; Biochemistry 32, 13123 (1993) Abstract
Calcium channel diversity and neurotransmitter release: the omega-conotoxins and omega-agatoxins: B.M. Olivera, et al.; Ann. Rev. Biochem. 63, 823 (1994) Abstract
Exocytotic Ca2+ channels in mammalian central neurons: K. Dunlap, et al.; TINS 18, 89 (1995), (Review) Abstract
P/Q-type Ca2+ channel blocker omega-agatoxin IVA protects against brain injury after focal ischemia in rats: K. Asakura, et al.; Brain Res. 776, 140 (1997) Abstract
Agatoxin-IVA-sensitive calcium channels mediate the presynaptic and postsynaptic nicotinic activation of cardiac vagal neurons: J. Wang, et al.; J. Neurophysiol. 85, 164 (2001) Abstract
Further Categories Containing This Product:
Ca2+ Channels (P/Q-type)
 
 
ALX-350-315 Revised 03-Apr-08
Agelasine D
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Natural Products with Antibiotic Activity
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-350-315-M001   1 mg 185.00 USD Add To Cart
Product Specification
FORMULA: C26H40N5
MW: 422.6
CAS NUMBER: 92664-80-7
SOURCE/HOST: Isolated from the sponge Agelas nakamurai.
PURITY: ≥97% (HPLC)
APPEARANCE: White to off-white solid.
SOLUBILITY: Soluble in DMSO or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
IDENTITY: Identity determined by 1H-NMR, 13C-NMR and MS.

Product Description
Displays broad spectrum of antibacterial activities. Antineoplastic compound. Associated with contractive responses of smooth muscles and inhibition of Na+/K+-ATPase.
Product Specific Literature References
(+)-agelasine D: improved synthesis and evaluation of antibacterial and cytotoxic activities: A. Vik, et al.; J. Nat. Prod. 69, 381 (2006) Abstract
Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs: A. Vik, et al.; Bioorg. Med. Chem. 15, 4016 (2007) Abstract
Further Categories Containing This Product:
Antitumor Agents (Anti-proliferative) • Na+/K+-ATPase/Related Products • Natural Products - Antitumor Reagents • Antibiotics - ATPase Inhibitors
 
 
ALX-350-326 Revised 29-May-07
Agelongine
Add to Clipboard
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Natural Products for Neurological Research
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-350-326-M001   1 mg 160.00 USD Add To Cart
Product Specification
FORMULA: C13H11BrN2O4
MW: 339.1
CAS NUMBER: 163564-84-9
SOURCE/HOST: Isolated from the sponge Agelas longissima.
PURITY: ≥97% (HPLC)
APPEARANCE: Yellow to brown solid.
SOLUBILITY: Soluble in DMSO or 100% ethanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
IDENTITY: Identity determined by 1H-NMR, 13C-NMR and MS.

Product Description
Alkaloid exhibiting antagonistic activity on serotonin receptors.
Product Specific Literature References
A novel bromopyrrole alkaloid from the sponge agelas longissima with antiserotonergic activity: F. Cafieri, et al.; Bioorg. Med. Chem. Lett. 5, 799 (1995)
Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent: L. Meijer, et al.; Chem. Biol. 7, 51 (2000) Abstract