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ALX-101-010
Revised 11-Sep-07
L-Aspartic acid
SYNONYMS
H-L-Asp-OH
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
L-Amino Acids
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
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ALX-101-010-G001
1 g
12.00 USD
Product Specification
FORMULA:
C
4
H
7
NO
4
MW:
133.1
CAS NUMBER:
56-84-8
MERCK INDEX:
14:
840
RTECS:
CI9098500
PURITY:
≥99.5%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Excitatory Amino Acids
•
NMDA Receptors/Related Products
ALX-101-011
Revised 22-Nov-06
D-Aspartic acid
SYNONYMS
H-D-Asp-OH
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
D-Amino Acids
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-101-011-G001
1 g
12.00 USD
Product Specification
FORMULA:
C
4
H
7
NO
4
MW:
133.1
CAS NUMBER:
1783-96-6
MERCK INDEX:
14:
840
RTECS:
CI9097500
PURITY:
≥99%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Excitatory Amino Acids
•
NMDA Receptors/Related Products
ALX-101-016
Revised 22-Nov-06
L-Glutamine
SYNONYMS
H-L-Gln-OH
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
L-Amino Acids
Ordering Information
Product Numbers:
Format:
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ALX-101-016-G005
5 g
12.00 USD
Product Specification
FORMULA:
C
5
H
10
N
2
O
3
MW:
146.2
CAS NUMBER:
56-85-9
MERCK INDEX:
14:
4471
RTECS:
MA2275100
PURITY:
≥98%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in water or dilute aqueous acid.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Excitatory Amino Acids
ALX-101-017
Revised 24-Jun-08
D-Glutamine
SYNONYMS
H-D-Gln-OH
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
D-Amino Acids
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-101-017-G001
1 g
32.00 USD
Product Specification
FORMULA:
C
5
H
10
N
2
O
3
MW:
146.2
CAS NUMBER:
5959-95-5
PURITY:
≥98% (TLC)
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in water (50mg/ml) or dilute aqueous acid.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
IDENTITY:
Identity determined by IR.
Further Categories Containing This Product:
Excitatory Amino Acids
ALX-101-018
Revised 30-Jan-06
L-Glutamic acid
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
L-Amino Acids
Ordering Information
Product Numbers:
Format:
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ALX-101-018-G001
1 g
12.00 USD
Product Specification
FORMULA:
C
5
H
9
NO
4
MW:
147.1
CAS NUMBER:
56-86-0
MERCK INDEX:
14:
4469
RTECS:
LZ9700000
PURITY:
≥99%
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Excitatory Amino Acids
•
Nitric Oxide Pathway Other Products
ALX-445-006
Revised 03-Dec-07
4α-Phorbol 12,13-didecanoate
SYNONYMS
4α-PDD
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Phorbols/Phorbol Esters
Ordering Information
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ALX-445-006-M001
1 mg
35.00 USD
ALX-445-006-M005
5 mg
110.00 USD
Product Specification
FORMULA:
C
40
H
64
O
8
MW:
672.9
CAS NUMBER:
27536-56-7
PURITY:
≥98% (HPLC)
APPEARANCE:
Lyophilized.
SOLUBILITY:
Soluble in DMSO, methanol, 100% ethanol, acetone, ether or dimethyl formamide.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stock solution cannot be made in aqueous media. Compound must be dissolved in an organic solvent prior to dilution into aqueous media. Add calculated volume of organic solvent to vial to prepare concentrated stock solution. Intermediate dilutions into the same organic solvent are recommended prior to final dilution into aqueous media.
HANDLING:
Protect from light.
HAZARD:
HIGHLY IRRITANT. VERY TOXIC. MAY BE CARCINOGENIC.
Product Description
Activator of TRPV4. Negative control for phorbol 12,13-didecanoate (PDD) (Prod. No.
ALX-445-002
).
Product Specific Literature References
TRPV4 calcium entry channel: a paradigm for gating diversity
:
B. Nilius, et al.; Am. J. Physiol. Cell Physiol.
286
, C195 (2004)
Abstract
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives
:
H. Watanabe, et al.; J. Biol. Chem.
277
, 13569 (2002)
Abstract
Related Products
ALX-445-002
Phorbol 12,13-didecanoate
Further Categories Containing This Product:
TRPV2, TRPV3, TRPV4/Related Products
•
Natural Products for Neurological Research
ALX-106-023
Revised 13-Dec-02
5-Hydroxy-L-tryptophan
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
Serotonergics & Serotonin Receptors/Related Products
Ordering Information
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ALX-106-023-M500
500 mg
20.00 USD
Product Specification
FORMULA:
C
11
H
12
N
2
O
3
MW:
220.2
CAS NUMBER:
56-69-9
APPEARANCE:
White solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from light.
Product Description
Serotonin precursor.
Further Categories Containing This Product:
Special Amino Acids
•
Glutamate Receptors (Metabotropic)/Related Products
ALX-106-024
Revised 06-Jun-06
O-Phospho-L-serine
SYNONYMS
L-Phosphoserine
L-Serine-O-phosphate
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
NMDA Receptors/Related Products
Ordering Information
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ALX-106-024-G001
1 g
10.00 USD
Product Specification
FORMULA:
C
3
H
8
NO
6
P
MW:
185.1
CAS NUMBER:
407-41-0
PURITY:
≥97%
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Store tightly sealed. Use fresh solutions.
Product Description
L-AP4 agonist. Competitive NMDA antagonist. Has affinity for type IV, but not type I, metabotropic glutamate receptor.
Product Specific Literature References
L-phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific L-glutamate receptor subtypes:
W.E. Klunk, et al.; J. Neurochem.
56
, 1997 (1991)
Abstract
Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor:
C. Thomsen & P.D. Suzdak; Neuroreport
4
, 1099 (1993)
Abstract
Agonists and antagonists for metabotropic glutamate receptors:
P.L. Ornstein, et al.; Curr. Pharm. Design
1
, 355 (1995), (Review)
Decreased expression of the metabotropic glutamate receptor-4 gene is associated with neuronal apoptosis:
K. Borodezt & S.R. D'Mello; J. Neurosci. Res.
53
, 531 (1998)
Abstract
Further Categories Containing This Product:
Special Amino Acids
•
Glutamate Receptors (Metabotropic)/Related Products
ALX-106-025
Revised 07-May-03
γ-Aminobutyric acid
SYNONYMS
GABA
PRODUCT LINE
Neurobiology
PRODUCT CATEGORY
GABA-ergics & GABA Receptors/Related Products
Ordering Information
Product Numbers:
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ALX-106-025-G010
10 g
7.00 USD
Product Specification
FORMULA:
C
4
H
9
NO
2
MW:
103.1
CAS NUMBER:
56-12-2
MERCK INDEX:
14:
430
PURITY:
≥99%
APPEARANCE:
White solid.
SOLUBILITY:
Soluble in water; slightly soluble in ethanol; insoluble in most organic solvents.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
Further Categories Containing This Product:
Special Amino Acids
ALX-106-028
Revised 03-Apr-08
D-Cycloserine
SYNONYMS
R(+)-4-Amino-3-isoxazolidinone
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Natural Products for Neurological Research
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-106-028-M050
50 mg
20.00 USD
ALX-106-028-M250
250 mg
80.00 USD
Product Specification
FORMULA:
C
3
H
6
N
2
O
2
MW:
102.1
CAS NUMBER:
68-41-7
RTECS:
NY2975000
SOURCE/HOST:
Synthetic.
PURITY:
≥97%
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Hygroscopic.
Product Description
Excitatory amino acid. Partial agonist at the glycine modulatory site of the NMDA receptor.
Further Categories Containing This Product:
Excitatory Amino Acids
•
Special Amino Acids
•
NMDA Receptors/Related Products
ALX-106-035
Revised 13-Dec-02
4-Hydroxy-D-phenylglycine
PRODUCT LINE
Combinatorial Chemistry
PRODUCT CATEGORY
Special Amino Acids
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-106-035-G001
1 g
20.00 USD
Product Specification
FORMULA:
C
8
H
9
NO
3
MW:
167.2
CAS NUMBER:
22818-40-2
PURITY:
≥99%
APPEARANCE:
White powder.
SOLUBILITY:
Soluble in alkalies.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+20°C
HAZARD:
IRRITANT.
Further Categories Containing This Product:
Excitatory Amino Acids
ALX-106-037
Revised 09-Oct-07
L-Cycloserine
SYNONYMS
S(-)-4-Amino-3-isoxazolidinone
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Natural Products for Neurological Research
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-106-037-M025
25 mg
50.00 USD
ALX-106-037-M100
100 mg
150.00 USD
Product Specification
FORMULA:
C
3
H
6
N
2
O
2
MW:
102.1
CAS NUMBER:
339-72-0; 4834-58-6
MERCK INDEX:
14:
2751
RTECS:
NY2976000
PURITY:
≥98%
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Hygroscopic. </
