ALEXIS Biochemicals: Neurogranin (28-43)

ALX-163-004

Revised 06-Jun-03

Neurogranin (28-43)
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	PKC Substrates

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-163-004-M001		1 mg	120.00 USD

Product Specification

SEQUENCE:	H-Ala-Ala-Lys-Ile-Gln-Ala-Ser-Phe-Arg-Gly-His-Met-Ala-Arg-Lys-Lys-OH
FORMULA:	C₇₈H₁₃₄N₂₈O₁₉S
MW:	1800.2
PURITY:	≥97%
APPEARANCE:	White lyophilized powder.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Peptide derived from the neurogranin phosphorylation domain. Highly selective substrate for protein kinase C (PKC), but very poor substrate for Ca²⁺/calmodulin-dependent kinase II and cAMP-dependent kinase (PKA).

Product Specific Literature References

Studies with synthetic peptide substrates derived from the neuronal protein neurogranin reveal structural determinants of potency and selectivity for protein kinase C: S.-J. Chen, et al.; Biochemistry 32, 1032 (1993) Abstract

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