• Home
  • Sitemap
  • Help
  • Technical Support
  • Contact
New Products
You are here: Home > New Products
Toolbar - View Selection
 
 Items 1-20 of 154 Page 1 of 8 Select Page: 1 2 3 4 5 6 7 8  >>  
AG-G0832 Revised 22-Apr-08 New product
GPX3 (mouse) ELISA Kit
Add to Clipboard
SYNONYMS Glutathione Peroxidase 3 (mouse) ELISA Kit
PRODUCT LINE Oxidative Stress
PRODUCT CATEGORY Oxidative Stress Markers & Reagents / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-G0832EK-KI01   96 wells 620.00 USD Add To Cart
AG-G0832TP-KI01 Twin Plex 2x96 wells 880.00 USD Add To Cart
AG-G0832PP-KI01 Penta Plex 5x96 wells 1'870.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SENSITIVITY: 150pg/ml (range 0 to 64ng/ml)
SPECIFICITY: Does not cross-react with human or rat sera.
APPLICATION: For the quantitative determination of GPX3 in mouse serum, plasma or cell culture supernatants.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
ELISA & EIA Kits
 
 
AG-N0812 Revised 05-Sep-08 New product
Nampt/Visfatin (mouse) (IntraCellular) ELISA Kit
Add to Clipboard
SYNONYMS Nicotinamide Phosphoribosyltransferase (mouse) (IntraCellular) ELISA Kit
PBEF1 (mouse) (IntraCellular) ELISA Kit
Pre-B-Cell Colony Enhancing Factor 1 (mouse) (IntraCellular) ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Visfatin / Nampt / PBEF / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-N0812EK-KI01   96 wells 640.00 USD Add To Cart
AG-N0812TP-KI01 Twin Plex 2x96 wells 940.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SENSITIVITY: 50pg/ml (range 0 to 64ng/ml)
SPECIFICITY: Does not cross-react with human or rat Nampt/visfatin.
APPLICATION: For the quantitative determination of Nampt/visfatin in mouse cell lysates.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
ELISA & EIA Kits • NAD+ Metabolism / Related Products
 
 
AG-N0823 Revised 26-Aug-08 New product
Nampt/Visfatin (human) (IntraCellular) ELISA Kit
Add to Clipboard
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Visfatin / Nampt / PBEF / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-N0823EK-KI01   96 wells 640.00 USD Add To Cart
AG-N0823TP-KI01 Twin Plex 2x96 wells 940.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 30pg/ml (range 0 to 32ng/ml)
SPECIFICITY: Does not cross-react with mouse sera.
APPLICATION: For the quantitative determination of Nampt/Visfatin in human cell lysates.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
ELISA & EIA Kits • NAD+ Metabolism / Related Products
 
 
AG-VN0812 Revised 07-Jul-08 New product
Nampt/Visfatin (mouse) ELISA Kit
Add to Clipboard
SYNONYMS Nicotinamide Phosphoribosyltransferase (mouse) ELISA Kit
PBEF1 (mouse) ELISA Kit
Pre-B-Cell Colony Enhancing Factor 1 (mouse) ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Visfatin / Nampt / PBEF / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-VN0812EK-KI01   96 wells 660.00 USD Add To Cart
AG-VN0812TP-KI01 Twin Plex 2x96 wells 920.00 USD Add To Cart
AG-VN0812PP-KI01 Penta Plex 5x96 wells 2'050.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SENSITIVITY: 50pg/ml (range 0 to 64ng/ml)
SPECIFICITY: Does not cross-react with human or rat Nampt/visfatin.
APPLICATION: For the quantitative determination of mouse Nampt/visfatin in serum.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
ELISA & EIA Kits • NAD+ Metabolism / Related Products
 
 
ALX-162-034 Revised 03-Jul-08 New product
MALP-2 (BULK)
Add to Clipboard
SYNONYMS Macrophage-activating Lipopeptide-2
S-[2,3-bis(Palmityloxy)-(2R)-propyl-cysteinyl-GNNDESNISFKEK]
PRODUCT LINE Inflammation
PRODUCT CATEGORY TLR Agonists Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-162-034-C500   500 µg 1'250.00 USD Add To Cart
Product Specification
FORMULA: C99H167N19O30S
MW: 2135.2
SOURCE/HOST: Synthetic.
CONCENTRATION: 1mg/ml
PURITY DETAIL: HPLC purified
FORMULATION: Liquid. Pyrogen-free, sterile solution in 33% (v/v) 2-propanol/water.
BIOLOGICAL ACTIVITY: Stimulates macrophages, monocytes and other TLR2 and TLR6 expressing cells in vitro at pg/ml concentrations (e.g. mouse macrophages: 50pg/ml; fibroblasts: 2ng/ml) to release various mediators. Human monocytes require about 10-100x higher concentrations for optimal cytokine or chemokine release than mouse PECS (see [12]). In vivo active at 0.5-5μg (e.g 0.5μg/20g mouse). The presence of 50mM octyl glucoside as carrier gives rise to a higher activity.
SHIPPING: SHIPPED ON DRY ICE
SHORT TERM STORAGE: -20°C
LONG TERM STORAGE: -80°C
USE/STABILITY: Stable for at least 3 years when stored at -20°C. This stock solution is stable for many months when kept in the refrigerator. MALP-2 solutions in the presene of carrier (50mM octyl glucoside, see Background/Technical Information below) are stable at +4°C at least 6 weeks. Some (10%) decrease of activity may occur shortly after transfer into new vessels. This is not due to decomposition but to adsorption (see below). Storage at room temperature for short periods of time does not influence bioactivity. When deep-frozen, MALP-2 does not loose activity within years.
HANDLING: Avoid freeze/thaw cycles. Avoid accidental injection, extreme care should be taken with hypodermic syringes. Avoid inhalation and prevent this compound from entering the bloodstream.
HAZARD: TOXIC.
Product Description
MALP-2 was originally isolated from Mycoplasma fermentans. This MALP-2 corresponds to the originally isolated isomer, which expresses potent endotoxin-like activity and approaches in certain experimental systems the toxicity of LPS. For description of the stereochemistry of MALP-2 (see [7]). MALP-2 signalling, unlike that of LPS, is not transduced via TLR4, but is induced via TLR2 and TLR6 signalling.
For more information about MALP-2 see www.malp-research.de.
New BULK size (500μg) of biologically active, pyrogen-free and sterile MALP-2 for in vitro and animal in vivo studies.
Product Specific Literature References
[1] Purification and partial biochemical characterization of a Mycoplasma fermentans-derived substance that activates macrophages to release nitric oxide, tumor necrosis factor, and interleukin-6: P.F. Muhlradt and M. Frisch; Infect. Immun. 62, 3801 (1994) Abstract
[2] Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration: P.F. Mühlradt, et al.; J. Exp. Med. 185, 1951 (1997) Abstract; Full Text
[3] MALP-2, a Mycoplasma lipopeptide with classical endotoxic properties: end of an era of LPS monopoly?: C. Galanos, et al.; J. Endotox. Res. 6, 471 (2000) Abstract
[4] Discrimination of bacterial lipoproteins by Toll-like receptor 6: O. Takeuchi, et al.; Int. Immunol. 13, 933 (2001) Abstract
[5] In vivo effects of a synthetic 2-kilodalton macrophage-activating lipopeptide of Mycoplasma fermentans after pulmonary application: A. Luhrmann, et al.; Infect. Immun. 70, 3785 (2002) Abstract; Full Text
[6] The Mycoplasma-derived lipopeptide MALP-2 is a potent mucosal adjuvant: F. Rharbaoui, et al.; Eur. J. Immunol. 32, 2857 (2002) Abstract
[7] Differential recognition of structural details of bacterial lipopeptides by toll-like receptors: M. Morr, et al.; Eur. J. Immunol. 32, 3337 (2002) Abstract
[8] CD14 is required for MyD88-independent LPS signaling: Z. Jiang, et al.; Nat. Immunol. 6, 565 (2005) Abstract
[9] The tumor suppressor CYLD Acts as a Negative Regulator for Toll-like Receptor 2 Signaling via Negative Cross-talk with TRAF6 and TRAF7: H. Yoshida, et al.; J. Biol. Chem. 280, 41111 (2005) Abstract; Full Text
[10] IRF-7 is the master regulator of type-I interferon-dependent immune responses: K. Honda, et al.; Nature 434, 772 (2005) Abstract
[11] The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies: N. Satta, et al.; Blood 109, 1507 (2007) Abstract
[12] Induction of cytokines and chemokines in human monocytes by Mycoplasma fermentans-derived lipoprotein MALP-2: A. Kaufmann, et al.; Infect. Immun. 67, 6303 (1999) Abstract; Full Text
General Information
BACKGROUND/TECHNICAL INFORMATION MALP-2 sticks avidly to glass or plastic. Since it is active at very low concentrations, i.e. at high dilutions, these low amounts of material tend to become adsorbed to pipette tips and plastic or glass containers. To avoid this, prepare several dilution steps of the MALP-2 stock solution with medium containing 5% autologous serum or buffers with 2% HSA. The presence of 50mM octyl glucoside in the first dilution step is often beneficial and gives rise to higher activity. Avoid small volumes in large vessels. Do not filter.
Because of the ester-bound fatty acids, MALP-2 is sensitive to alkali or acid. The medium should be preconditioned in the CO2 incubator in order to ensure that the pH does not become alkaline. Add cells in preconditioned medium as soon as possible and incubate.
MANUFACTURER Licensed from GBF Braunschweig, Germany.
General Literature References
Synergic effects of mycoplasmal lipopeptides and extracellular ATP on activation of macrophages: T. Into, et al.; Infect. Immun. 70, 3586 (2002) Abstract; Full Text
Site-specific proteolysis of the MALP-404 lipoprotein determines the release of a soluble selective lipoprotein-associated motif-containing fragment and alteration of the surface phenotype of Mycoplasma fermentans: K.L. Davis & K.S. Wise; Infect. Immun. 70, 1129 (2002) Abstract; Full Text
Related Products
Further Categories Containing This Product:
Peptides
 
 
ALX-167-028 Revised 28-Jul-08 New product
Blocking Peptide for PAb to SorLA (IC) (Prod. No. ALX-215-060)
Add to Clipboard
PRODUCT LINE Immunology
PRODUCT CATEGORY Blocking Peptides
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-167-028-C050   50 µg 150.00 USD Add To Cart
Product Specification
SEQUENCE: CE2198DAPMITGFSDDVPMVIA2215
MW: 2010.3
CONCENTRATION: 0.2mg/ml
PURITY: ≥95%
FORMULATION: Liquid. In TBS containing 0.1% BSA and 0.02% sodium azide.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Description
Synthetic peptide corresponding to the 18 C-terminal amino acids of mouse SorLA with an added N-terminal cysteine.
Related Products
 
 
ALX-168-009/1 Revised 22-Jul-08 New product
L-TAT Control Peptide (for Prod. No. ALX-159-600)
Add to Clipboard
SYNONYMS JNK Inhibitor 1 (L-stereoisomer) Control Peptide (for Prod. No. ALX-159-600)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY JNK [SAPK1] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-168-009/1-R050   50 µl 40.00 USD Add To Cart
Product Specification
SEQUENCE: GRKKRRQRRR-amide
FORMULA: C55H109N31O12
MW: 1396.6
CONCENTRATION: 10mM
PURITY: ≥85% (HPLC)
FORMULATION: Liquid. Sterile solution in water.
SHIPPING: SHIPPED ON DRY ICE
LONG TERM STORAGE: -80°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C. Keep on ice at all times.
Product Description
Control peptide for L-JNKI. For more details see L-JNKI1 (Prod.No. ALX-159-600).
Product Specific Literature References
Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death: C. Bonny, et al.; Diabetes 50, 77 (2001) Abstract; Full Text
Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation: R. Reinehr, et al.; FASEB J. 17, 731 (2003) Abstract; Full Text
Related Products
Further Categories Containing This Product:
Peptides
 
 
ALX-168-009F Revised 28-Jul-08 New product
L-TAT Control Peptide (for Prod. No. ALX-159-600) (FITC)
Add to Clipboard
SYNONYMS JNK Inhibitor 1 (L-stereoisomer) Control Peptide (for Prod. No. ALX-159-600) (FITC)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY JNK [SAPK1] / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-168-009F-R050 FITC 50 µl 110.00 USD Add To Cart
Product Specification
SEQUENCE: FITC-β-A-RKKRRQRRRA-amide
FORMULA: C80H128N34O17S
MW: 1870.2
CONCENTRATION: 1mM
PURITY: ≥90% (HPLC)
FORMULATION: Liquid. In sterile PBS.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. Keep on ice at all times.
Product Description
Control peptide for L-JNKI. For more details see L-JNKI1 (Prod.No. ALX-159-600).
Product Specific Literature References
Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death: C. Bonny, et al.; Diabetes 50, 77 (2001) Abstract; Full Text
Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation: R. Reinehr, et al.; FASEB J. 17, 731 (2003) Abstract; Full Text
Related Products