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Nitric Oxide Scavengers
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ALX-430-001 Revised 30-Nov-06
Carboxy-PTIO
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SYNONYMS 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide . potassium salt
PRODUCT LINE Nitric Oxide Pathway
PRODUCT CATEGORY Nitric Oxide Scavengers
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-430-001-M010   10 mg 40.00 USD Add To Cart
ALX-430-001-M050   50 mg 160.00 USD Add To Cart
ALX-430-001-M250   250 mg 580.00 USD Add To Cart
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Product Specification
FORMULA: C14H16N2O4 . K
MW: 276.3 . 39.1
CAS NUMBER: 148819-94-7
PURITY: ≥98%
APPEARANCE: Blue solid.
SOLUBILITY: Soluble in 100% ethanol, methanol, DMSO or dimethyl formamide. Highly soluble in water or aqueous buffers, e. g. PBS, pH 7.2.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Water soluble and stable nitric oxide radical scavenger that shows in chemical and biological systems antagonistic action against the free nitric oxide radical (NO·). The inhibitory effects were almost 2-fold stronger than those of NMMA (Prod. No. ALX-106-001) and NOARG (Prod. No. ALX-105-001). Reacts with nitric oxide in a stoichometric manner. Can be used for an improved detection of nitric oxide in activated macrophage cultures in combination with the Griess reagent (Prod. No. ALX-400-004).
Product Specific Literature References
Antagonistic action of imidazolineoxyl N-oxides against endothelium- derived relaxing factor/.NO through a radical reaction: T. Akaike, et al.; Biochemistry 32, 827 (1993) Abstract
Pronounced enhancement of .NO-dependent antimicrobial action by an .NO- oxidizing agent, imidazolineoxyl N-oxide: K. Yoshida, et al.; Infect. Immun. 61, 3552 (1993) Abstract
Therapeutic effects of imidazolineoxyl N-oxide against endotoxin shock through its direct nitric oxide-scavenging activity: M. Yoshida, et al.; BBRC 202, 923 (1994) Abstract
Improved detection of nitric oxide radical (NO.) production in an activated macrophage culture with a radical scavenger, carboxy PTIO and Griess reagent: F. Amano & T. Noda; FEBS Lett. 368, 425 (1995) Abstract
Nitric oxide activation of guanylyl cyclase in cells revisited: B. Roy & J. Garthwaite; PNAS 103, 12185 (2006) Abstract
 
 
ALX-385-003 Revised 03-Apr-08
Cyanidin chloride
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SYNONYMS 3,3',4',5,7-Pentahydroxy-flavylium chloride
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Flavonoids/Related Products
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ALX-385-003-M010   10 mg 195.00 USD Add To Cart
ALX-385-003-M050   50 mg 780.00 USD Add To Cart
Product Specification
FORMULA: C15H11ClO6
MW: 322.7
CAS NUMBER: 528-58-5
MERCK INDEX: 14: 2687
RTECS: LK9824000
PURITY: ≥97%
APPEARANCE: Dark red to black solid.
SOLUBILITY: Soluble in methanol or 0.1% hydrochloric acid.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
IDENTITY: Identity determined by 1H-NMR, 13C-NMR and MS.

Product Description
Antioxidant flavonoid. Nitric oxide (NO) scavenger.
Product Specific Literature References
Flavonoids as scavengers of nitric oxide radical: S.A.B.E. Acker, et al.; BBRC 214, 755 (1995) Abstract
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radical Biol. & Med. 20, 933 (1996), (Review) Abstract
Dietary flavonoids: bioavailability, metabolic effects, and safety: J.A. Ross & C.M. Kasum; Annu. Rev. Nutr. 22, 19 (2002), (Review) Abstract
Cyanidins: metabolism and biological properties: F. Galvano, et al.; J. Nutr. Biochem. 15, 2 (2004), (Review) Abstract
Further Categories Containing This Product:
Nitric Oxide Scavengers • Natural Products - Antioxidants • Natural Products - Nitric Oxide Pathway Modulators • Active Substances from Fruit and Vegetables
 
 
ALX-385-014 Revised 19-Nov-07
Pelargonidin chloride
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Flavonoids/Related Products
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ALX-385-014-M005   5 mg 135.00 USD Add To Cart
Product Specification
FORMULA: C15H11O5Cl
MW: 306.7
CAS NUMBER: 134-04-3
MERCK INDEX: 14: 7071
PURITY: ≥97% (HPLC)
APPEARANCE: Red to brown solid.
SOLUBILITY: Soluble in 100% ethanol or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C

Product Description
Antioxidant flavonoid. Nitric oxide scavenger.
Product Specific Literature References
Flavonoids as scavengers of nitric oxide radical: S.A.B.E. Acker, et al.; BBRC 214, 755 (1995) Abstract
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radical Biol. & Med. 20, 933 (1996), (Review) Abstract
Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin: Y. Noda, et al.; J. Agric. Food Chem. 50, 166 (2002) Abstract
Antigenotoxic effects of the phytoestrogen pelargonidin chloride and the polyphenol chlorogenic acid: S.K. Abraham, et al.; Mol. Nutr. Food Res. 51, 880 (2007) Abstract
Further Categories Containing This Product:
Nitric Oxide Scavengers • Natural Products - Nitric Oxide Pathway Modulators • Natural Products - Antioxidants • Active Substances from Fruit and Vegetables
 
 
ALX-430-007 Revised 17-Mar-05
PTIO
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SYNONYMS 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide
PRODUCT LINE Nitric Oxide Pathway
PRODUCT CATEGORY Nitric Oxide Scavengers
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ALX-430-007-M025   25 mg 30.00 USD Add To Cart
ALX-430-007-M100   100 mg 90.00 USD Add To Cart
Product Specification
FORMULA: C13H17N2O2
MW: 233.3
CAS NUMBER: 18390-00-6
PURITY: ≥98%
APPEARANCE: Blue crystals.
SOLUBILITY: Soluble in methanol, 100% ethanol or water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
HAZARD: IRRITANT.

Product Description
Stable nitric oxide (NO) radical scavenger.
Product Specific Literature References
Antagonistic action of imidazolineoxyl N-oxides against endothelium- derived relaxing factor/.NO through a radical reaction: T. Akaike, et al.; Biochemistry 32, 827 (1993) Abstract
Enhanced vascular permeability in solid tumor is mediated by nitric oxide and inhibited by both new nitric oxide scavenger and nitric oxide synthase inhibitor: H. Maeda, et al.; Jpn. J. Cancer Res. 85, 331 (1994) Abstract
 
 
ALX-460-028 Revised 24-Oct-07
Rutin . trihydrate
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SYNONYMS Quercetin-3-rutinoside . 3H2O
Vitamin P
3,3',4',5,7-Pentahydroxyflavone-3-rutinoside . 3H2O
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Flavonoids/Related Products
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ALX-460-028-G005   5 g 15.00 USD Add To Cart
Product Specification
FORMULA: C27H30O16 . 3H2O
MW: 610.5 . 54.0
CAS NUMBER: 153-18-4
MERCK INDEX: 14: 8304
PURITY: ≥99% (Assay)
APPEARANCE: Off-white to yellow powder.
SOLUBILITY: Soluble in pyridine or alkaline solutions; slightly soluble in 100% ethanol; very slightly soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +20°C
HANDLING: Protect from light.
HAZARD: IRRITANT.

Product Description
Antioxidant flavonoid. Nitric oxide (NO) scavenger.
Product Specific Literature References
Flavonoids as scavengers of nitric oxide radical: S.A.B.E. Acker, et al.; BBRC 214, 755 (1995) Abstract
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radical Biol. & Med. 20, 933 (1996), (Review) Abstract
Antioxidant and chelating properties of flavonoids
: L.G. Korkina and I.B. Afanas´ev; Adv. Pharmacol. 38, 151 (1997) Abstract
Antimicrobial activity of flavonoids: T. P. Cushnie & A. J. Lamb; Int. J. Antimicrob. Agents 26, 343 (2005) Abstract
Further Categories Containing This Product:
Nitric Oxide Scavengers • Natural Products - Nitric Oxide Pathway Modulators • Natural Products - Chemopreventive Agents • Natural Products - Antioxidants • Active Substances from Fruit and Vegetables
 
 
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