ALEXIS Biochemicals: Nomilin

ALX-350-228

Revised 08-Jul-08

Nomilin
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Chemopreventive Agents

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-228-M025		25 mg	105.00 USD

Product Specification

FORMULA:	C₂₈H₃₄O₉
MW:	514.6
CAS NUMBER:	1063-77-0
MERCK INDEX:	14: 6674
SOURCE/HOST:	Isolated from grapefruit seed and citrus juice.
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in acetone; slightly soluble in 100% ethanol, methanol, isopropanol or ethyl acetate; insoluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C

Product Description

Induces phase II detoxifying enzymes and inhibits chemically induced carcinogenesis. Exhibits immunomodulatory activity and also inhibits HIV-1 replication. Does not possess any inherent antioxidant capacity.

Product Specific Literature References

V.P. Maier, et al.; ACS Symposium Series 143, 63 (1980)
Inhibition of benzo[a]pyrene-induced forestomach neoplasia in mice by citrus limonoids: L.K.T. Lam & S. Hasegawa; Nutr. Cancer 12, 43 (1989) Abstract
The effect of citrus limonoids on hamster buccal pouch carcinogenesis: E.G. Miller, et al.; Carcinogenesis 10, 1535 (1989) Abstract
Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system: T.J. Raphael & G. Kuttan; Phytomedicine 10, 483 (2003) Abstract
Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells: L. Battinelli, et al.; Planta Med. 69, 910 (2003) Abstract
Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside: A.P. Breksa, 3rd & G.D. Manners; J. Agric. Food Chem. 54, 3827 (2006) Abstract

Further Categories Containing This Product:

Antitumor Agents (Enzyme Activators & Inducers) • Natural Products - Immunomodulators • Natural Products - Antiviral / anti-HIV Agents • Active Substances from Fruit and Vegetables

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