ALEXIS Biochemicals: O-Phospho-L-serine

ALX-106-024

Revised 06-Jun-06

O-Phospho-L-serine
SYNONYMS	L-Phosphoserine L-Serine-O-phosphate
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	NMDA Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-106-024-G001		1 g	10.00 USD

Product Specification

FORMULA:	C₃H₈NO₆P
MW:	185.1
CAS NUMBER:	407-41-0
PURITY:	≥97%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Store tightly sealed. Use fresh solutions.

Product Description

L-AP4 agonist. Competitive NMDA antagonist. Has affinity for type IV, but not type I, metabotropic glutamate receptor.

Product Specific Literature References

L-phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific L-glutamate receptor subtypes: W.E. Klunk, et al.; J. Neurochem. 56, 1997 (1991) Abstract
Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor: C. Thomsen & P.D. Suzdak; Neuroreport 4, 1099 (1993) Abstract
Agonists and antagonists for metabotropic glutamate receptors: P.L. Ornstein, et al.; Curr. Pharm. Design 1, 355 (1995), (Review)
Decreased expression of the metabotropic glutamate receptor-4 gene is associated with neuronal apoptosis: K. Borodezt & S.R. D'Mello; J. Neurosci. Res. 53, 531 (1998) Abstract

Further Categories Containing This Product:

Special Amino Acids • Glutamate Receptors (Metabotropic) / Related Products

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