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ALX-210-454
Revised 16-May-07
Polyclonal Antibody to Omentin 1 (human)
SYNONYMS
anti-Intelectin-1 (human) PAb
anti-Intestinal Lactoferrin Receptor (human) PAb
anti-Galactofuranose-binding Lectin (human) PAb
anti-Endothelial Lectin HL-1 (human) PAb
PRODUCT LINE
Obesity & Adipokines
PRODUCT CATEGORY
Omentin/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-454-C100
100 µg
340.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Purified IgG.
FORMULATION:
Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Synthetic peptide corresponding to aa 95-115 (T
95
VGDRWSSQQGSKADYPEGDG
115
) of human omentin 1 (intelectin-1).
SPECIFICITY:
Recognizes human omentin 1.
APPLICATION:
ELISA
(direct and indirect: 1:2’000-1:5’000)
Western Blot
(1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been recently identified as a novel visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.
MANUFACTURER
Manufactured by AdipoGen, Inc.
Related Products
ALX-201-371
Omentin 1 (human) (recombinant) (His)
ALX-210-941
Polyclonal Antibody to Omentin 1 (AT117)
ALX-522-108
Omentin 1 (human) (recombinant)
ALX-804-850
Monoclonal Antibody to Omentin 1 (human) (Saly-1)
ALX-804-852
Monoclonal Antibody to Omentin 1 (Saly-2)
APO-54N-026
Omentin 1 (human) Detection Set [For ELISA Application]
APO-54N-034
Omentin 1 (human) ELISA Kit
Further Categories Containing This Product:
PI(3)K-Akt-mTOR Pathway Other Products
•
Polyclonal Antibodies
ALX-210-942
Revised 16-May-07
Polyclonal Antibody to Omentin 2 (human) (AT119)
SYNONYMS
anti-Intelectin-2 (human) PAb (AT119)
anti-Endothelial Lectin HL-2 (human) PAb (AT119)
PRODUCT LINE
Obesity & Adipokines
PRODUCT CATEGORY
Omentin/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-942-C100
100 µg
360.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Protein A-affinity purified.
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Recombinant human omentin 2 (intelectin-2) (aa 158-325).
SPECIFICITY:
Recognizes human omentin 2.
APPLICATION:
ELISA
Immunoprecipitation
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-358
Revised 30-Jul-07
Polyclonal Antibody to Perilipin A (mouse)
PRODUCT LINE
Obesity & Adipokines
PRODUCT CATEGORY
Perilipins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-358-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
PURITY DETAIL:
Purified IgG.
FORMULATION:
Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 502-517 (E
502
PILGRTQYSQLRKKS
517
) of rat perilipin A. This sequence is 93% conserved in human perilipin A.
SPECIFICITY:
Recognizes mouse perilipin A. Detects a band of ~62kDa by Western blot.
APPLICATION:
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-053
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysisv
:
D.L. Brasaemle, et al.; J. Biol. Chem.
275
, 38486 (2000)
Abstract
;
Full Text
Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes
:
G.M. Clifford, et al.; J. Biol. Chem.
275
, 5011 (2000)
Abstract
;
Full Text
Peripheral signals conveying metabolic information to the brain: short-term and long-term regulation of food intake and energy homeostasis
:
P.J. Havel; Exp. Biol. Med. (Maywood)
226
, 963 (2001)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-359
Revised 06-Jun-06
Polyclonal Antibody to Perilipin A/B (mouse)
PRODUCT LINE
Obesity & Adipokines
PRODUCT CATEGORY
Perilipins/Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-359-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
Purified IgG.
FORMULATION:
Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 1-17 (M
1
SMNKGPTLLDGDLPEQ
17
) of rat perilipin A and B. This sequence is 82% conserved in human perilipin.
SPECIFICITY:
Recognizes mouse perilipin A and B. Detects bands of ~62kDa (perilipin A) and ~46kDa (perilipin B) by Western blot.
APPLICATION:
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-054
.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis
:
D.L. Brasaemle, et al.; J. Biol. Chem.
275
, 38486 (2000)
Abstract
;
Full Text
Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes
:
G.M. Clifford, et al.; J. Biol. Chem.
275
, 5011 (2000)
Abstract
;
Full Text
Peripheral signals conveying metabolic information to the brain: short-term and long-term regulation of food intake and energy homeostasis
:
P.J. Havel; Exp. Biol. Med. (Maywood)
226
, 963 (2001)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-117
Revised 24-Feb-05
Polyclonal Antibody to PPAR
SYNONYMS
anti-Peroxisome Proliferator Activated Receptor PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
PPAR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-117-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Antiserum diluted in PBS containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 484-498 (I
484
KKTETDMSLHPLLQ
498
) of the C-terminal domain of rat PPARγ2 (peroxisome proliferator activated receptor γ2). This sequence is completely conserved in human, mouse, rat, bovine, chicken and pig PPARγ1, PPARα and NUC1.
SPECIFICITY:
Recognizes mouse and rat PPARγ2. Detects a band of ~55 kDa by Western blot. Cross-reacts with recombinant rat PPARα in Western blot and recombinant mouse PPARγ1 in immunoprecipitation.
APPLICATION:
Gel Supershift Assay
Immunoprecipitation
Western Blot (1:2'000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer:
P. Tontonoz, et al.; Genes Dev.
8
, 1224 (1994)
Abstract
Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
:
O. Braissant, et al.; Endocrinology
137
, 354 (1996)
Abstract
MCF-7 and T47D human breast cancer cells contain a functional peroxisomal response
:
M.W. Kilgore, et al.; Mol. Cell Endocrinol.
129
, 229 (1997)
Abstract
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-190/1
Revised 30-Oct-06
Polyclonal Antibody to PPARα (mouse)
SYNONYMS
anti-Peroxisome Proliferator Activated Receptor α (mouse) PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
PPAR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-190/1-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. Contains 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 1-18 (M
1
VDTESPICP
LSPLEADD
18
) of mouse PPARα
(peroxisome proliferator activated receptor α). A single aa substitution (I
8
to L
8
) exists between the mouse and human protein.
SPECIFICITY:
Recognizes mouse PPARα. Detects a band of ~52kDa by Western blot. Does not cross-react with PPARδ or PPARγ.
APPLICATION:
Immunocytochemistry (1:100)
Immunoprecipitation
Western Blot (1:1’000)
Functional Application (inhibits PPARα DNA binding)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-029
.
Related Products
ALX-165-029
Blocking Peptide for PAb to PPARα (mouse) (Prod. No.
ALX-210-190/1
)
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-361
Revised 26-Feb-07
Polyclonal Antibody to PPARα (mouse) (phosphorylated) (pSer12)
SYNONYMS
anti-Peroxisome Proliferator Activated Receptor α (mouse (phosphorylated) (pSer
12
) PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
PPAR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-361-C100
100 µg
385.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS contanining 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 8-19 (I
8
CPLpSPLEADDL
19
) of mouse PPARα (peroxisome proliferator activated receptor α) phosphorylated at Ser
12
.
SPECIFICITY:
Recognizes mouse PPARα phosphorylated at Ser
12
. Detects a band of ~52 kDa by Western blot.
APPLICATION:
Western Blot (2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-055
.
Product Specific Literature References
MCF-7 and T47D human breast cancer cells contain a functional peroxisomal response
:
M.W. Kilgore, et al.; Mol. Cell Endocrinol.
129
, 229 (1997)
Abstract
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes
:
R.M. Lavinsky, et al.; PNAS
95
, 2920 (1998)
Abstract
;
Full Text
Related Products
ALX-165-055
Blocking Peptide for PAb to PPARα (mouse) (phosphorylated) (pSer
12
) (Prod. No.
ALX-210-361
)
Further Categories Containing This Product:
Phospho-specific Antibodies
•
Polyclonal Antibodies
ALX-210-362
Revised 09-Feb-05
Polyclonal Antibody to PPARα (mouse) (phosphorylated) (pSer21)
SYNONYMS
anti-Peroxisome Proliferator Activated Receptor α (mouse) (phosphorylated) (pSer
21
) PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
PPAR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-362-C100
100 µg
385.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Epitope affinity purified IgG in PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 14-25 (L
14
EADDLEpSPLSE
25
) of mouse PPARα (peroxisome proliferator activated receptor α) phosphorylated at Ser
21
.
SPECIFICITY:
Recognizes mouse PPARα phosphorylated at Ser
21
. Detects a band of ~52kDa by Western blot.
APPLICATION:
Western Blot (2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-056
.
Product Specific Literature References
MCF-7 and T47D human breast cancer cells contain a functional peroxisomal response
:
M.W. Kilgore, et al.; Mol. Cell Endocrinol.
129
, 229 (1997)
Abstract
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes
:
R.M. Lavinsky, et al.; PNAS
95
, 2920 (1998)
Abstract
;
Full Text
Related Products
ALX-165-056
Blocking Peptide for PAb to PPARα
(mouse) (phosphorylated) (pSer
21
)
(Prod. No.
ALX-210-362
)
Further Categories Containing This Product:
Phospho-specific Antibodies
•
Polyclonal Antibodies
ALX-210-225
Revised 24-Feb-06
Polyclonal Antibody to PPARγ
SYNONYMS
anti-Peroxisome Proliferator Activated Receptor γ PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
PPAR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-225-1
1 Vial
412.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
PURITY DETAIL:
Affinity purified IgG.
FORMULATION:
Liquid. In TBS, pH 7.4, containing 50% glycerol, 0.5mg/ml BSA and 0.02% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 82-101 (P
82
ASPPYYSEKTQLYNKPHEE
101
) of human PPARγ1
(peroxisome proliferator activated receptor g1)
and to
aa 110-129 of human PPARγ
2.
SPECIFICITY:
Recognizes human and mouse PPARγ1 and PPARγ2. Detects bands of ~53kDa and ~57kDa by Western blot.
APPLICATION:
Immunohistochemistry (1:200)
Immunoprecipitation (5µg per reaction)
Western Blot
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
Further Categories Containing This Product:
Polyclonal Antibodies
ALX-210-192
Revised 12-Oct-05
Polyclonal Antibody to PPARγ2 (mouse)
SYNONYMS
anti-Peroxisome Proliferator Activated Receptor γ2 (mouse) PAb
PRODUCT LINE
DNA Regulation / Transcription
PRODUCT CATEGORY
PPAR Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-192-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml.
PURITY DETAIL:
Epitope-affinity purified IgG.
FORMULATION:
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 1-16 (M
1
GETLGDSPIDPESDS
16
) of human PPARγ2 (peroxisome proliferator activated receptor γ2).
SPECIFICITY:
Recognizes mouse PPARγ2. Detects a band of ~56kDa by Western blot. Does not cross-react with PPARα or PPARδ.
APPLICATION:
Gel Supershift Assay
Immunohistochemistry (1:500)
Western Blot (1:500)
Functional Application (inhibits PPARγ2 DNA binding)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-031
.
Product Specific Literature References
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes
:
R.M. Lavinsky, et al.; PNAS
95
, 2920 (1998)
Abstract
;
Full Text
Delayed activation of PPARgamma by LPS and IFN-gamma attenuates the oxidative burst in macrophages
:
A.A. Von Knethen & B. Brune; FASEB J.
15
, 535 (2001)
Abstract
;
Full Text
Activation of peroxisome proliferator-activated receptor gamma by nitric oxide in monocytes/macrophages down-regulates p47phox and attenuates the respiratory burst
:
A. Von Knethen & B. Brune; J. Immunol.
169
, 2619 (2002)
Abstract
;
Full Text
A human peripheral blood monocyte-derived subset acts as pluripotent stem cells
:
Y. Zhao, et al.; PNAS
100
, 2426 (2003)
Abstract
;
Full Text
