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Obesity & Adipokines
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ALX-804-580 Revised 20-Jan-06
Monoclonal Antibody to Growth Hormone (human) (g3H5)
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SYNONYMS anti-GH (human) MAb (g3H5)
anti-Somatotropin (human) MAb (g3H5)
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Growth Hormones/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-580-R050   50 µl 195.00 USD Add To Cart
ALX-804-580-R100   100 µl 320.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: g3H5
ISOTYPE: Mouse IgG2b
CONCENTRATION: 1mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS, pH 7.4, containing 0.1% sodium azide.
IMMUNOGEN: Recombinant human GH (growth hormone).
SPECIFICITY: Recognizes human GH.
APPLICATION: ELISA
Western Blot (1:500-1:1'000)
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 1 month when stored at +4°C.
HANDLING: Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies • Obesity & Diabetes Other Products • Tumor Markers
 
 
ALX-804-520 Revised 31-Oct-06
Monoclonal Antibody to Leptin (human) (HLEP 55G)
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SYNONYMS anti-OB Gene Product (human) MAb (HLEP 55G)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Leptin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-520-C050   50 µg 195.00 USD Add To Cart
ALX-804-520-C100   100 µg 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: HLEP 55G
ISOTYPE: Mouse IgG2b
CONCENTRATION: 1mg/ml.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human leptin.
SPECIFICITY: Recognizes human leptin.
APPLICATION: ELISA (direct and indirect: 1:5'000-1:10'000)
Western Blot (1:5'000-1:10'000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-702 Revised 31-Oct-06
Monoclonal Antibody to Leptin (human) (HLEP 155)
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SYNONYMS anti-OB Gene Product (human) MAb (HLEP 155)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Leptin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-702-C050   50 µg 195.00 USD Add To Cart
ALX-804-702-C100   100 µg 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: HLEP 155
ISOTYPE: Mouse IgG1
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human leptin.
SPECIFICITY: Recognizes both natural and recombinant human leptin. Detects a band of ~16kDa by Western blot. Does not cross-react with mouse or rat leptin.
APPLICATION: ELISA (direct and indirect: 1:5'000-1:10'000).
Western Blot (1:2'000-1:10'000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After receipt, prepare aliquots and store at -20°C.
Product Images
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-701 Revised 31-Oct-06
Monoclonal Antibody to Leptin (rat) (RLEP 227)
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SYNONYMS anti-OB Gene Product (rat) MAb (RLEP 227)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Leptin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-701-C050   50 µg 195.00 USD Add To Cart
ALX-804-701-C100   100 µg 270.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Rat
CLONE: RLEP 227
ISOTYPE: Mouse IgG2a
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant rat leptin.
SPECIFICITY: Recognizes both natural and recombinant rat leptin. Detects a band of ~16kDa by Western blot. Does not cross-react with human or mouse leptin.
APPLICATION: ELISA (direct and indirect: 1:5'000-1:10'000).
Western Blot (1:5'000-1:10'000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
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General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-717 Revised 24-Jun-08
Monoclonal Antibody to Nampt/Visfatin (OMNI379)
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SYNONYMS anti-Nicotinamide Phosphoribosyltransferase MAb (OMNI379)
anti-PBEF1 MAb (OMNI379)
anti-Pre-B-Cell Colony Enhancing Factor 1 MAb (OMNI379)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Visfatin/Nampt/PBEF/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-717-C050   50 µg 195.00 USD Add To Cart
ALX-804-717-C100   100 µg 270.00 USD Add To Cart
ALX-804-717B-C050 Biotin 50 µg 380.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
CLONE: OMNI379
ISOTYPE: Mouse IgG2a
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant human Nampt/visfatin.
SPECIFICITY: Recognizes human, mouse and rat Nampt/visfatin. Detects a band of ~54kDa by Western blot.
APPLICATION: ELISA (direct and indirect: 1:2’000-1:5’000)
Immunohistochemistry (paraffin sections (1:500-1:1'000))
Western Blot (1:2’000-1:5’000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature)
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for 1-2 weeks when stored at +4°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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Product Specific Literature References
Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1: S.K. Bae, et al.; FEBS Lett. 580, 4105 (2006) Abstract
Molecular Characteristics of Serum Visfatin and Differential Detection by Immunoassays: A. Korner, et al.; J. Clin. Endocrinol. Metab. 92, 4783 (2007) Abstract; Full Text
Nampt/PBEF/Visfatin Regulates Insulin Secretion in beta Cells as a Systemic NAD Biosynthetic Enzyme: J.R. Revollo, et al.; Cell. Metab. 6, 363 (2007) Abstract
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
Related Products
Further Categories Containing This Product:
Monoclonal Antibodies • NAD+ Metabolism/Related Products
 
 
ALX-804-854 Revised 29-Oct-07
Monoclonal Antibody to Nesfatin-1 (Nesfaty-1)
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PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Food Intake Modulators Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-854-C100   100 µg 360.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
CLONE: Nesfaty-1
ISOTYPE: Mouse IgG1
SOURCE/HOST: Purified from concentrated hybridoma tissue cell culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant rat nesfatin-1 (aa 25-106) (Prod. No. ALX-522-118).
SPECIFICITY: Recognizes mouse and rat nesfatin-1 and precursor nucleobindin-2.
APPLICATION: ELISA
Immunoprecipitation (1:100)
Western Blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
General Information
Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the regulation of the feeding behaviour. Intracerebroventricular injection of nesfatin-1 reduces body weight in rat by affecting the animal food intake.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Identification of nesfatin-1 as a satiety molecule in the hypothalamus: I.S. Oh, et al.; Nature 443, 709 (2006) Abstract
Related Products
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-804-852 Revised 28-Apr-08
Monoclonal Antibody to Omentin 1 (Saly-2)
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SYNONYMS anti-Intelectin-1 MAb (Saly-2)
anti-Intestinal Lactoferrin Receptor MAb (Saly-2)
anti-Galactofuranose-binding Lectin MAb (Saly-2)
anti-Endothelial Lectin HL-1 MAb (Saly-2)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Omentin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-852-C100   100 µg 360.00 USD Add To Cart
ALX-804-852B-C100 Biotin 100 µg 390.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Rat
CLONE: Saly-2
ISOTYPE: Mouse IgG2a
SOURCE/HOST: Purified from concentrated hybridoma tissue cell culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human omentin 1 (intelectin-1) (aa 17-231).
SPECIFICITY: Recognizes human omentin 1 and rat omentin. Cross-reacts with human omentin 2.
APPLICATION: ELISA (detection)
Western Blot (1:1'000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Keep conjugated formats at +4°C. Do not freeze. Protect from light.
General Information
Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been recently identified as a novel visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action: R.Z. Yang, et al.; Am. J. Physiol. Endocrinol. Metab. 290, E1253 (2006) Abstract
Related Products
Further Categories Containing This Product:
Monoclonal Antibodies • PI(3)K-Akt-mTOR Pathway Other Products
 
 
ALX-804-850 Revised 16-Aug-07
Monoclonal Antibody to Omentin 1 (human) (Saly-1)
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SYNONYMS anti-Intelectin-1 (human) MAb (Saly-1)
anti-Intestinal Lactoferrin Receptor (human) MAb (Saly-1)
anti-Galactofuranose-binding Lectin (human) MAb (Saly-1)
anti-Endothelial Lectin HL-1 (human) MAb (Saly-1)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Omentin/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-804-850-C100   100 µg 360.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: Saly-1
ISOTYPE: Mouse IgG2b
SOURCE/HOST: Purified from concentrated hybridoma tissue cell culture supernatant.
CONCENTRATION: 1mg/ml
PURITY: ≥95% (SDS-PAGE)
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human omentin 1 (intelectin-1) (aa 17-231).
SPECIFICITY: Recognizes human omentin 1.
APPLICATION: ELISA (capture)
Immunohistochemistry (paraffin sections)
Western Blot (1:1’000)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
Please click on thumbnails to enlarge.
General Information
Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been recently identified as a novel visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action: R.Z. Yang, et al.; Am. J. Physiol. Endocrinol. Metab. 290, E1253 (2006) Abstract
Related Products
Further Categories Containing This Product:
Monoclonal Antibodies • PI(3)K-Akt-mTOR Pathway Other Products