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N-Acetylneuraminic Acid/Derivatives
You are here: Product Lines > Neurobiology > Sphingolipids & Glycosphingolipids/Related Products > N-Acetylneuraminic Acid/Derivatives
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ALX-305-010 Revised 10-Dec-04
N-Acetylneuraminic acid
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SYNONYMS NANA
Sialic acid
Neu5Ac
5-Acetylamino-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Carbohydrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-305-010-M050   50 mg 30.00 USD Add To Cart
ALX-305-010-M250   250 mg 95.00 USD Add To Cart
Product Specification
FORMULA: C11H19NO9
MW: 309.3
CAS NUMBER: 131-48-6
MERCK INDEX: 14: 8484
SOURCE/HOST: Synthetic.
PURITY: ≥97%
APPEARANCE: White to light pink powder.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable between pH 4.0 and 7.0 when frozen.
HANDLING: Protect from light.
Further Categories Containing This Product:
N-Acetylneuraminic Acid/Derivatives
 
 
ALX-270-343 Revised 30-May-07
3-O-Methyl-N-acetyl-D-glucosamine
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SYNONYMS 3-OMe-GlcNAc
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Carbohydrates
Ordering Information
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ALX-270-343-M005   5 mg 190.00 USD Add To Cart
Product Specification
FORMULA: C9H17NO6
MW: 235.2
CAS NUMBER: 94825-74-8
PURITY: ≥98% (1H-NMR)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in DMSO (10mg/ml) or water (10mg/ml).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
HAZARD: HARMFUL.

Product Description
Inhibitor of N-acetylglucosamine kinase (Ki=17µM) and N-acetylmannosamine kinase (Ki=80µM). It has been found that 3-OMe-GlcNAc potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine.
Product Specific Literature References
Inhibition of N-acetylglucosamine kinase and N-acetylmannosamine kinase by 3-O-methyl-N-acetyl-D-glucosamine in vitro: R. Zeitler, et al.; Eur. J. Biochem. 204, 1165 (1992) Abstract
Utility of 3-O-methyl-N-acetyl-D-glucosamine, an N-acetylglucosamine kinase inhibitor, for accurate assay of glucokinase in pancreatic islets and liver: I. Miwa, et al.; Enzyme Protein 48, 135 (1994) Abstract
Further Categories Containing This Product:
N-Acetylneuraminic Acid/Derivatives • Obesity & Diabetes Other Products
 
 
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