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Items 11 of 11
ALX-350-344
Revised 03-Apr-08
Actinotetraose Hexatiglate
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-350-344-M001
1 mg
140.00 USD
Product Specification
FORMULA:
C
54
H
78
O
27
MW:
1159.2
CAS NUMBER:
216590-44-2
SOURCE/HOST:
Isolated from
Amycolatopsis
sp. MST-AS5902.
PURITY:
≥95% (HPLC)
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in methanol, dimethyl formamide or DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Unique tetrasaccharide with six tiglate esters. Shows no significant antimicrobial activity.
Product Specific Literature References
Structure of actinotetraose hexatiglate, a unique glucotetraose from an actinomycete bacterium:
R.W. Rickards, et al.; J. Antibiot. (Tokyo)
51
, 1093 (1998)
Abstract
;
Full Text
Further Categories Containing This Product:
Carbohydrates
ALX-350-151
Revised 21-May-08
Agistatine B
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-350-151-M001
1 mg
90.00 USD
ALX-350-151-M005
5 mg
360.00 USD
Product Specification
FORMULA:
C
11
H
18
O
4
MW:
214.3
CAS NUMBER:
144096-46-8
SOURCE/HOST:
Isolated from fungus FH-A 6239.
PURITY:
≥98% (
1
H-NMR)
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in methanol, DMSO or acetone.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
A tricyclic analog of agistatine A, which has been described as an inhibitor of cholesterol biosynthesis.
Product Specific Literature References
Secondary Metabolites by Chemical Screening, 29:
A. Zeeck, et al.; Liebigs Ann. 627 (1996)
Related Products
ALX-350-163
Agistatine D
Further Categories Containing This Product:
Cholesterol & Lipid Transport / Related Products
ALX-350-163
Revised 15-Sep-08
Agistatine D
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-350-163-M001
1 mg
90.00 USD
ALX-350-163-M005
5 mg
360.00 USD
Product Specification
FORMULA:
C
11
H
14
O
4
MW:
210.2
CAS NUMBER:
144096-47-9
SOURCE/HOST:
Isolated from fungus FH-A 6239.
PURITY:
≥98% (HPLC)
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in DMSO or acetone.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
IDENTITY:
Identity determined by
1
H-NMR.
Product Description
Analog of agistatine A, which has been described as an inhibitor of cholesterol biosynthesis.
Product Specific Literature References
Secondary Metabolites by Chemical Screening, 29:
A. Zeeck, et al.; Liebigs Ann.
1996
, 627
Related Products
ALX-350-151
Agistatine B
Further Categories Containing This Product:
Cholesterol & Lipid Transport / Related Products
ALX-350-160
Revised 03-Sep-08
Aloeresin A
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-350-160-M001
1 mg
185.00 USD
Product Specification
FORMULA:
C
28
H
28
O
11
MW:
540.5
CAS NUMBER:
74545-79-2
SOURCE/HOST:
Isolated from
Aloe
sp.
PURITY:
≥97% (HPLC)
APPEARANCE:
Brown solid.
SOLUBILITY:
Soluble in DMSO or 100% ethanol.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from light.
IDENTITY:
Identity determined by
1
H-NMR and MS.
Product Description
Metabolite of aloesin (Prod. No. ALX-350-158). Inhibits α-glucosidases.
Product Specific Literature References
Metabolism of aloesin and related compounds by human intestinal bacteria: a bacterial cleavage of the C-glucosyl bond and the subsequent reduction of the acetonyl side chain:
Q.M. Che, et al.; Chem. Pharm. Bull. (Tokyo)
39
, 704 (1991)
Abstract
Geographical variation in the major compounds of Aloe ferox leaf exudate:
B.E. van Wyk, et al.; Planta Med.
61
, 250 (1995)
Abstract
High-performance liquid chromatographic profiles of aloe constituents and determination of aloin in beverages, with reference to the EEC regulation for flavouring substances:
F. Zonta, et al.; J. Chromatogr. A.
718
, 99 (1995)
Abstract
Determination of aloesin and aloeresin A for the detection of aloe in beverages:
M. DellAgli, et al.; J. Agric. Food Chem.
55
, 3363 (2007)
Abstract
A reversed-phase high-performance liquid chromatographic method for the determination of aloesin, aloeresin A and anthraquinone in Aloe ferox:
M. Zahn, et al.; Phytochem. Anal.
19
, 122 (2008)
Abstract
alpha-Glucosidase inhibitor from Chinese aloes:
N. Jong-Anurakkun, et al.; Fitoterapia
79
, 456 (2008)
Abstract
Related Products
ALX-350-158
Aloesin
Further Categories Containing This Product:
Glycosidases / Related Products
ALX-380-262
Revised 09-Apr-08
Amidepsine A
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-380-262-M001
1 mg
230.00 USD
ALX-380-262-MM25
2.5 mg
470.00 USD
Product Specification
FORMULA:
C
29
H
29
NO
11
MW:
567.6
SOURCE/HOST:
Isolated from fungal strain FO-2943.
PURITY:
≥95% (HPLC)
APPEARANCE:
Pale white to pale yellow powder.
SOLUBILITY:
Soluble in methanol or ethyl acetate; insoluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC
50
=10.2µM) and Raji cells (IC
50
=15.5µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Product Specific Literature References
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties:
H. Tomoda, et al.; J. Antibiot.
48
, 937 (1995)
Abstract
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C:
H. Tomoda, et al.; J. Antibiot.
48
, 942 (1995)
Abstract
General Information
MANUFACTURER
Fungal strain courtesy of the Kitasato Institute, Tokyo.
Related Products
ALX-380-263
Amidepsine D
Further Categories Containing This Product:
Lipid Metabolism Other Products
ALX-380-263
Revised 09-Apr-08
Amidepsine D
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-380-263-M001
1 mg
230.00 USD
ALX-380-263-MM25
2.5 mg
470.00 USD
Product Specification
FORMULA:
C
26
H
24
O
10
MW:
496.5
SOURCE/HOST:
Isolated from fungal strain FO-2943.
PURITY:
≥95% (HPLC)
APPEARANCE:
White to light pink powder.
SOLUBILITY:
Soluble in methanol (1mg/ml); insoluble in water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC
50
=17.5µM) and Raji cells (IC
50
=2.8µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Product Specific Literature References
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties:
H. Tomoda, et al.; J. Antibiot.
48
, 937 (1995)
Abstract
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C:
H. Tomoda, et al.; J. Antibiot.
48
, 942 (1995)
Abstract
General Information
MANUFACTURER
Fungal strain courtesy of the Kitasato Institute, Tokyo.
Related Products
ALX-380-262
Amidepsine A
Further Categories Containing This Product:
Lipid Metabolism Other Products
ALX-380-132
Revised 15-Sep-08
Aspinonene
SYNONYMS
6,7-Epoxy-5-hydroxymethyl-3-octen-2,5-diol
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-380-132-M001
1 mg
60.00 USD
ALX-380-132-M005
5 mg
240.00 USD
Product Specification
FORMULA:
C
9
H
16
O
4
MW:
188.2
CAS NUMBER:
157676-96-5
SOURCE/HOST:
Isolated from
Aspergillus ochraceus
(DSM-7428)
.
PURITY:
≥95%
APPEARANCE:
Oil.
SOLUBILITY:
Soluble in DMSO or methanol.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
IDENTITY:
Identity determined by
1
H-NMR.
Product Description
Low molecular weight fungal metabolite. Polyfunctional natural product.
Product Specific Literature References
Aspinonene, a new multifunctional fungal metabolite:
J. Fuchser, et al.; Liebigs Ann. Chem.
1994
, 831
Biosynthesis of aspinonene, a branched pentaketide produced by aspergillus ochraceus, related to aspyrone:
J. Fuchser, et al.; J. Chem. Soc. Perkin Trans.
13
, 1663 (1995)
Pentaketides relating to aspinonene and dihydroaspyrone from a marine-derived fungus, Aspergillus ostianus:
K. Kito, et al.; J. Nat. Prod.
70
, 2022 (2007)
Abstract
ALX-350-164
Revised 30-Sep-08
Curvulin
SYNONYMS
Ethyl 2-acetyl-3,5-dihydroxyphenylacetate
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-350-164-M001
1 mg
90.00 USD
ALX-350-164-M005
5 mg
360.00 USD
Product Specification
FORMULA:
C
12
H
14
O
5
MW:
238.2
SOURCE/HOST:
Isolated from
Senecio steetzii
.
PURITY:
≥96% (HPLC)
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in methanol, DMSO or acetone.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
IDENTITY:
Identity determined by
1
H-NMR.
Product Description
Phytotoxin.
Product Specific Literature References
Studies in the biochemistry of microorganisms-I Curvulin and curvulinic acid, metabolic products of curvularia siddiqui:
A. Kamal, et al.; Tetrahedron
18
, 433 (1962)
Abstract
Studies in the biochemistry of micro-organisms-II Constitution of curvulin, curvulinic acid and curvulol, metabolic products of curvularia siddiqui:
A. Kamal, et al.; Tetrahedron
19
, 111 (1963)
Abstract
Studies in the biochemistry of micro-organisms—VI *1 The structure and stereochemistry of the phthalan curvulol, and other metabolic products of curvularia siddiqui:
A. Kamal, et al.; Tetrahedron
23
, 3801 (1967)
Abstract
Curvulin and O-Methylcurvulinic acid: Phytotoxic metabolites of Drechslera indica which cause necroses on purslane and spiny amaranth:
D. Kenfield, et al.; Plant Sci.
60
, 123 (1989)
Abstract
Production of phenylacetic acid derivatives and 4-epiradicinol in culture by Curvularia lunata:
G.B. Varma, et al.; Phytochemistry
67
, 1925 (2006)
Abstract
Further Categories Containing This Product:
Pesticides / Related Products
ALX-380-133
Revised 16-Sep-08
Decarestrictine D
SYNONYMS
Tuckolide
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-380-133-M001
1 mg
70.00 USD
ALX-380-133-M005
5 mg
280.00 USD
Product Specification
FORMULA:
C
10
H
16
O
5
MW:
216.2
CAS NUMBER:
127393-89-9, 141846-71-1
SOURCE/HOST:
Isolated from
Penicillium
sp
.
PURITY:
≥98%
APPEARANCE:
White to off-white solid.
SOLUBILITY:
Soluble in methanol, acetone or DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
IDENTITY:
Identity determined by
1
H-NMR.
Product Description
Shows hypolipidemic activity
in vivo.
Inhibitor of cholesterol biosynthesis
in vitro.
Product Specific Literature References
Secondary metabolites by chemical screening. 8. Decarestrictines, a new family of inhibitors of cholesterol biosynthesis from Penicillium. I. Strain description, fermentation, isolation and properties:
S. Grabley, et al.; J. Antibiot.
45
, 56 (1992)
Abstract
Secondary metabolites by chemical screening. 9. Decarestrictines, a new family of inhibitors of cholesterol biosynthesis from Penicillium. II. Structure elucidation of the decarestrictines A to D:
A. Göhrt, et al.; J. Antibiot.
45
, 66 (1992)
Abstract
Chemical investigation of the metabolites from the Canadian tuckahoe, Polyporus tuberaster:
W.A. Ayer, et al.; J. Nat. Prod.
55
, 649 (1992)
Abstract
A non-enzymatic reaction in the late biosynthesis of the decarestrictine family:
M. Mayer & R. Thiericke; J. Antibiot.
46
, 1372 (1993)
Abstract
Synthesis of Tuckolide, a New Cholesterol Biosynthesis Inhibitor:
M.B. Andrus & T.L. Shih; J. Org. Chem.
61
, 8780 (1996)
Abstract
Further Categories Containing This Product:
Cholesterol & Lipid Transport / Related Products
ALX-350-161
Revised 11-Aug-08
Macrosporin
SYNONYMS
1,7-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Other Natural Products
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ALX-350-161-M001
1 mg
150.00 USD
Product Specification
FORMULA:
C
16
H
12
O
5
MW:
284.3
CAS NUMBER:
22225-67-8
SOURCE/HOST:
Isolated from
Alternaria
sp.
PURITY:
≥97% (HPLC)
APPEARANCE:
Yellow solid.
SOLUBILITY:
Soluble in DMSO or 100% ethanol.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from light.
IDENTITY:
Identity determined by
1
H-NMR and MS.
Product Description
Anthraquinone.
Product Specific Literature References
Metabolites of Dactylaria lutea. The structures of dactylariol and the antiprotozoal antibiotic dactylarin:
A.M. Becker, et al.; J. Antibiot. (Tokyo)
31
, 324 (1978)
Abstract
High-performance liquid chromatographic determination of macrosporin, altersolanol A, alterporriol A, B and C in fermentation of Alternaria porri (Ellis) Ciferri:
R. Suemitsu, et al.; J. Chromatogr.
454
, 406 (1988)
Abstract
Biologically active polyketide metabolites from an undetermined fungicolous hyphomycete resembling Cladosporium:
U. Höller, et al.; J. Nat. Prod.
65
, 876 (2002)
Abstract
Natural occurrence of fungi and fungal metabolites in moldy tomatoes:
B. Andersen & J.C. Frisvad; J. Agric. Food Chem.
52
, 7507 (2004)
Abstract
New and cytotoxic anthraquinones from
