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Obesity & Adipokines
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ALX-380-263 Revised 09-Apr-08 New product
Amidepsine D
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Other Natural Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-380-263-M001   1 mg 230.00 USD Add To Cart
ALX-380-263-MM25   2.5 mg 470.00 USD Add To Cart
Product Specification
FORMULA: C26H24O10
MW: 496.5
SOURCE/HOST: Isolated from fungal strain FO-2943.
PURITY: ≥95% (HPLC)
APPEARANCE: White to light pink powder.
SOLUBILITY: Soluble in methanol (1mg/ml); insoluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=17.5µM) and Raji cells (IC50=2.8µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Product Specific Literature References
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties: H. Tomoda, et al.; J. Antibiot. 48, 937 (1995) Abstract
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C: H. Tomoda, et al.; J. Antibiot. 48, 942 (1995) Abstract
General Information
MANUFACTURER Fungal strain courtesy of the Kitasato Institute, Tokyo.
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Further Categories Containing This Product:
Lipid Metabolism Other Products
 
 
AG-A0722 Revised 15-Feb-08 New product
ANGPTL6 (human) ELISA Kit
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SYNONYMS Angiopoietin-like Protein 6 (human) ELISA Kit
AGF (human) ELISA Kit
Angiopoietin-related Growth Factor (human) ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-A0722EK-KI01   96 wells 640.00 USD Add To Cart
AG-A0722PP-KI01 Penta Plex 5x96 wells 1'880.00 USD Add To Cart
AG-A0722TP-KI01 Twin Plex 2x96 wells 940.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 1.2ng/ml (range 0 to 200ng/ml)
SPECIFICITY: Does not cross-react with mouse and rat sera.
APPLICATION: For the quantitative determination of ANGPTL6 in human serum, plasma or cell culture supernatants.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
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ELISA & EIA Kits
 
 
AG-A0822 Revised 03-Mar-08 New product
ANGPTL3 (human) ELISA Kit
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SYNONYMS Angiopoietin-like Protein 3 (human) ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-A0822EK-KI01   96 wells 640.00 USD Add To Cart
AG-A0822PP-KI01 Penta Plex 5x96 wells 1'880.00 USD Add To Cart
AG-A0822TP-KI01 Twin Plex 2x96 wells 940.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SENSITIVITY: 150pg/ml (range 0 to 20ng/ml)
SPECIFICITY: Does not cross-react with mouse and rat sera.
APPLICATION: For the quantitative determination of ANGPTL3 in human serum, plasma or cell culture supernatants.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
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Further Categories Containing This Product:
ELISA & EIA Kits
 
 
AG-DA0831 Revised 15-Feb-08 New product
ANGPTL3 (mouse/rat) Dual ELISA Kit
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SYNONYMS Angiopoietin-like Protein 3 (mouse/rat) Dual ELISA Kit
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
AG-DA0831EK-KI01   96 wells 640.00 USD Add To Cart
AG-DA0831PP-KI01 Penta Plex 5x96 wells 1'880.00 USD Add To Cart
AG-DA0831TP-KI01 Twin Plex 2x96 wells 940.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
Rat
SENSITIVITY: 15pg/ml (range 0 to 2ng/ml)
SPECIFICITY: Does not cross-react with human sera.
APPLICATION: For the quantitative determination of ANGPTL3 in mouse or rat serum, plasma or cell culture supernatants.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
General Information
MANUFACTURER Manufactured by AdipoGen, Inc.
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Further Categories Containing This Product:
ELISA & EIA Kits
 
 
ALX-201-387 Revised 09-Jul-08
ANGPTL1 (Fibrinogen-like Domain) (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 1 (Fibrinogen-like Domain) (human) (recombinant)
Angiopoietin-3 (Fibrinogen-like Domain) (human) (recombinant)
ANG-3 (Fibrinogen-like Domain) (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-387-C010   10 µg 290.00 USD Add To Cart
ALX-201-387-C050   50 µg 810.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Fibrinogen-like domain of human ANGPTL1 (angiopoietin-like protein 1) (aa 197-491) is fused at the N-terminus to a FLAG®-tag.
CONCENTRATION: 0.3mg/ml
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link O95841: Angiopoietin-related Protein 1 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-396 Revised 18-Mar-08
ANGPTL2 (Coiled-coil Domain) (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 2 (Coiled-coil Domain) (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-396-C010   10 µg 270.00 USD Add To Cart
ALX-201-396-C050   50 µg 790.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Coiled-coil domain of human ANGPTL2 (angiopoietin-like protein 2) (aa 23-248) is fused at the C-terminus to a FLAG®-tag.
CONCENTRATION:  
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q9UKU9: Angiopoietin-related protein 2 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-392 Revised 18-Mar-08
ANGPTL2 (Fibrinogen-like Domain) (human) (recombinant)
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SYNONYMS Angiopoietin-like Protein 2 (Fibrinogen-like Domain) (human) (recombinant)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
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Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-392-C010   10 µg 290.00 USD Add To Cart
ALX-201-392-C050   50 µg 810.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. Fibrinogen-like domain of human ANGPTL2 (angiopoietin-like protein 2) (aa 245-493) is fused at the N-terminus to a FLAG®-tag.
CONCENTRATION:  
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2µm-filtered solution in PBS.
ENDOTOXIN CONTENT: <0.1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
General Information
BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q9UKU9: Angiopoietin-related protein 2 (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER Manufactured by AdipoGen, Inc.
Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins
 
 
ALX-201-412 Revised 27-Mar-08 New product
ANGPTL3 (Coiled-coil Domain) (mouse) (recombinant) (His)
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SYNONYMS Angiopoietin-like Protein 3 (Coiled-coil Domain) (mouse) (recombinant) (His)
Angiopoietin-5 (Coiled-coil Domain) (mouse) (recombinant) (His)
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Angiopoietin-like Proteins [ANGPTLs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-201-412-C010   10 µg 350.00 USD Add To Cart
ALX-201-412-C050   50 µg 810.00 USD Add To Cart
Product Specification
SOURCE/HOST: Produced in HEK 293 cells. The signal peptide and the coiled-coil domain of mouse ANGPTL3 is fused at the C-terminus to a His-tag.
PURITY: ≥90% (SDS-PAGE)
FORMULATION: Liquid. 0.2μm-filtered solution in PBS.
ENDOTOXIN CONTENT: <1EU/µg protein (LAL-test).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Working aliquots are stable for up to 3 months when stored at -20°C.
HANDLING: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
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General Information
BACKGROUND/TECHNICAL INFORMATION Swiss-Prot link Q9R182: ANGPTL3 (mouse)
MANUFACTURER Manufactured by AdipoGen, Inc.
General Literature References
Identification of a mammalian angiopoietin-related protein expressed specifically in liver: D. Conklin, et al.; Genomics 62, 477 (1999) Abstract
ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase: T. Shimizugawa, et al.; J. Biol. Chem. 27, 33742 (2002) Abstract; Full Text
Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes: M. Shimamura, et al. ; Biochem. Biophys. Res. Commun. 301, 604 (2003) Abstract
ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states: K. Inukai; Biochem. Biophys. Res. Commun. 317, 1075 (2004) Abstract
Differential regulation and properties of angiopoietin-like proteins 3 and 4: H. Ge, et al.; J. Lipid Res. 46, 1484 (2005) Abstract
Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy: Y. Oike, et al.; Trends Mol. Med. 11, 473 (2005) Abstract
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Further Categories Containing This Product:
Recombinant Proteins/Fusion Proteins