ALEXIS Biochemicals: Ochratoxin A

ALX-630-089

Revised 16-Sep-08

Ochratoxin A
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Mycotoxins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-630-089-M001		1 mg	40.00 USD
ALX-630-089-M005		5 mg	150.00 USD
ALX-630-089-M025		25 mg	590.00 USD

Product Specification

FORMULA:	C₂₀H₁₈ClNO₆
MW:	403.8
CAS NUMBER:	303-47-9
MERCK INDEX:	14: 6740
RTECS:	AY4375000
SOURCE/HOST:	Isolated from Aspergillus ochraceus.
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white crystalline powder.
SOLUBILITY:	Soluble in methanol (10mg/ml).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HAZARD:	VERY TOXIC. MAY BE CARCINOGENIC. MAY BE TERATOGENIC. MAY BE MUTAGENIC.

Product Description

Mycotoxin. Natural contaminant of mouldy food and feed. It has a number of toxic effects, the most prominent being nephrotoxicity. Immunosuppressive, genotoxic, teratogenic and carcinogenic. Stimulates lipid peroxidation. Induces oxidative DNA lesions coupled with direct DNA adducts via quinone formation.

Product Specific Literature References

Ochratoxin A, a toxic metabolite produced by Aspergillus ochraceus Wilh: K.J. van der Merwe, et al.; Nature 205, 112 (1965) Abstract
Lipid peroxidation as a possible cause of ochratoxin A toxicity: A.D. Rahimtula, et al.; Biochem. Pharmacol. 37, 4469 (1988) Abstract
Mechanism of ochratoxin A stimulated lipid peroxidation: R.F. Omar, et al.; Biochem. Pharmacol. 40, 1183 (1990) Abstract
Role of cytochrome P-450 in ochratoxin A-stimulated lipid peroxidation: R.F. Omar, et al.; J. Biochem. Toxicol. 6, 203 (1991) Abstract
Effect of superoxide dismutase and catalase on the nephrotoxicity induced by subchronical administration of ochratoxin A in rats: I. Baudrimont, et al.; Toxicology 89, 101 (1994) Abstract
Toxicity and metabolism of ochratoxin A: J. Fink-Gremmels, et al.; Nat. Toxins 3, 214 (1995) Abstract
How aspartame prevents the toxicity of ochratoxin A: E.E. Creppy, et al.; J. Toxicol. Sci. 23 Supp. 2, 165 (1998) Abstract
Toxicokinetics and toxicodynamics of ochratoxin A, an update: D. Ringot, et al.; Chem. Biol. Interact. 159, 18 (2006), (Review) Abstract
Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans: A. Pfohl-Leszkowicz & R. A. Manderville; Mol. Nutr. Food Res. 51, 61 (2007), (Review) Abstract

Further Categories Containing This Product:

Lipid Peroxidation • Oxidative Stress Markers & Reagents / Related Products • Plant Research Reagents / Related Products

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.