ALEXIS Biochemicals: Olomoucine, Iso-

ALX-350-090

Revised 10-Mar-08

Olomoucine, Iso-
SYNONYMS	6-Benzylamino-2-(2-hydroxyethylamino)-7-methylpurine
PRODUCT LINE	Cell Cycle
PRODUCT CATEGORY	CDK & Cyclin Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-090-M005		5 mg	70.00 USD
ALX-350-090-M025		25 mg	280.00 USD

Product Specification

FORMULA:	C₁₅H₁₈N₆O
MW:	298.4
CAS NUMBER:	101622-50-8
PURITY:	≥98%
APPEARANCE:	Off-white solid.
SOLUBILITY:	Soluble in DMSO or methanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Inactive negative control for use in studies involving olomoucine (Prod. No. ALX-350-013).

Product Specific Literature References

Inhibition of cyclin-dependent kinases by purine analogues: J. Vesely, et al.; Eur. J. Biochem. 224, 771 (1994) Abstract
The cyclin-dependent kinase (cdk) inhibitors, olomoucine and roscovitine, alter the expression of a molluscan circadian pacemaker: N.A. Krucher, et al.; Cell. Mol. Neurobiol. 17, 495 (1997) Abstract
The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity: F. Alessi, et al.; Exp. Cell Res. 245, 8 (1998) Abstract
Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine: J.R. Taylor, et al.; PNAS 104, 4147 (2007) Abstract

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