ALEXIS Biochemicals: Omentin (rat) (recombinant)

ALX-522-132

Revised 27-Mar-08

Omentin (rat) (recombinant)
SYNONYMS	Intelectin-1 (rat) (recombinant) Intestinal Lactoferrin Receptor (rat) (recombinant) Galactofuranose-binding Lectin (rat) (recombinant) Endothelial Lectin HL-1 (rat) (recombinant)
PRODUCT LINE	Obesity & Adipokines
PRODUCT CATEGORY	Omentin / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-522-132-C010		10 µg	390.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Rat
MW:	~38-40kDa
SOURCE/HOST:	Produced in HEK 293 cells. Rat omentin (aa 20-313) is fused at the N-terminus to a FLAG^®-tag.
CONCENTRATION:	0.1mg/ml after reconstitution.
PURITY:	≥95% (SDS-PAGE)
FORMULATION:	Lyophilized. Contains PBS.
ENDOTOXIN CONTENT:	<0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION:	Reconstitute with 100µl sterile water.
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -20°C.
HANDLING:	Avoid freeze/thaw cycles.

General Information

Omentin (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been recently identified as a novel visceral fat (or omental fat) depot-specific adipokine. Omentin is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin triggers AKT signalling in the absence of insulin.
BACKGROUND/TECHNICAL INFORMATION	Swiss-Prot link Q499T8: Similar to intelectin (rat) FLAG is a registered trademark of Sigma-Aldrich Co.
MANUFACTURER	Manufactured by Apotech Corporation.

General Literature References

Human homologs of the Xenopus oocyte cortical granule lectin XL35: J.K. Lee, et al.; Glycobiology 11, 65 (2001) Abstract; Full Text
Molecular cloning and functional expression of a human intestinal lactoferrin receptor: Y.A. Suzuki, et al.; Biochemistry 40, 15771 (2001) Abstract
Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall: S. Tsuji, et al.; J. Biol. Chem. 276, 23456 (2001) Abstract; Full Text
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action: R.Z. Yang, et al.; Am. J. Physiol. Endocrinol. Metab. 290, E1253 (2006) Abstract; Full Text

Further Categories Containing This Product:

PI(3)K-Akt-mTOR Pathway Other Products • Recombinant Proteins / Fusion Proteins

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