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ALX-210-126
Revised 07-Aug-07
Polyclonal Antibody to Calreticulin
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Calreticulin / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-126-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Others
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Antiserum containing 0.05% sodium azide.
IMMUNOGEN:
Recombinant human calreticulin.
SPECIFICITY:
Recognizes human, mouse, rat, rabbit and monkey calreticulin.
APPLICATION:
Immunohistochemistry (1:100)
Immunocytochemistry
Immunoprecipitation
Western Blot (1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Images
Please click on thumbnails to enlarge.
Product Specific Literature References
Redistribution of intracellular Ca2+ stores during phagocytosis in human neutrophils:
O. Stendahl, et al.; Science
265
, 1439 (1994)
Abstract
Cell surface calreticulin is a putative mannoside lectin which triggers mouse melanoma cell spreading:
T.K. White, et al.; J. Biol. Chem.
270
, 15926 (1995)
Abstract
;
Full Text
Calreticulin interacts with newly synthesized human immunodeficiency virus type 1 envelope glycoprotein, suggesting a chaperone function similar to that of calnexin:
A. Otteken & B. Moss; J. Biol. Chem.
271
, 97 (1996)
Abstract
;
Full Text
Further Categories Containing This Product:
ER-Golgi Intermediate Compartment [ERGIC] / Related Products
•
Endoplasmatic Reticulum Stress
•
Polyclonal Antibodies
ALX-210-171
Revised 03-Jun-05
Polyclonal Antibody to Calreticulin (CT)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Calreticulin / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-171-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Dog
Others
SOURCE/HOST:
From chicken.
FORMULATION:
Liquid. Contains 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 399-414 (D
399
EKEEDEEESPGQAKD
414
) of mouse calreticulin.
SPECIFICITY:
Recognizes human, mouse, rat, rabbit, dog and hamster calreticulin. Detects a band of ~60kDa and and unidentified band of ~120kDa by Western blot.
APPLICATION:
Western Blot.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-153-016
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-153-016
Blocking Peptide for PAb to Calreticulin (CT) (Prod. No.
ALX-210-171
)
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
ER-Golgi Intermediate Compartment [ERGIC] / Related Products
•
Polyclonal Antibodies
ALX-210-170/1
Revised 19-May-08
Polyclonal Antibody to Calreticulin (NT)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Calreticulin / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-170/1-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Dog
Others
SOURCE/HOST:
From chicken.
CONCENTRATION:
1.1mg/ml
PURITY DETAIL:
Epitope-affinity purified IgY.
FORMULATION:
Liquid. Contains 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 24-43 (K
24
EQFLDGDAWTNRWVESKHK
43
) of mouse calreticulin.
SPECIFICITY:
Recognizes human, mouse, rat, dog and hamster calreticulin. Detects a band of ~60-66kDa by Western blot.
APPLICATION:
Immunocytochemistry
Western Blot (1:1’000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
BLOCKING PEPTIDE:
For Blocking Peptide See Prod. No.
ALX-153-017
.
Product Images
Please click on thumbnails to enlarge.
Related Products
ALX-153-017
Blocking Peptide for PAb to Calreticulin (NT) (Prod. No.
ALX-210-170/1
)
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
ER-Golgi Intermediate Compartment [ERGIC] / Related Products
•
Polyclonal Antibodies
ALX-210-808
Revised 05-Mar-07
Polyclonal Antibody to Caspase-4
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
Caspase Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-808-C100
100 µg
357.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
SOURCE/HOST:
From rabbit.
CONCENTRATION:
0.2mg/ml
PURITY DETAIL:
Affinity purified.
FORMULATION:
Liquid. In PBS, pH 7.2, containing 0.5% BSA, 0.01% thimerosal and 30% glycerol.
IMMUNOGEN:
Synthetic peptide corresponding to aa 85-101 of human caspase-4.
SPECIFICITY:
Recognizes human, mouse and rat procaspase-4. Detects a band of ~43kDa by Western blot.
APPLICATION:
Western Blot (1-2µg/ml).
Optimal conditions must be determined individually for each application.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
Polyclonal Antibodies
ALX-210-404
Revised 30-Oct-06
Polyclonal Antibody to ERp29
PRODUCT LINE
Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY
Protein Synthesis, Modification & Degradation Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-404-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
Rat
Dog
Monkey
Others
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Contains 0.02% sodium azide.
IMMUNOGEN:
Full length recombinant rat ERp29.
SPECIFICITY:
Recognizes human, mouse, rat, non-human primate, bovine, dog, hamster and guinea pig ERp29. Detects a band of ~29kDa by Western blot.
APPLICATION:
Immunocytochemistry (1:500)
Immunoprecipitation (1:500)
Western Blot (1:2'500)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
Polyclonal Antibodies
ALX-210-405
Revised 04-Dec-07
Polyclonal Antibody to ERp57 (human)
SYNONYMS
anti-PDIA3 (human) PAb
anti-Protein Disulfide Isomerase A3 (human) PAb
PRODUCT LINE
Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY
Protein Synthesis, Modification & Degradation Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-405-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Contains 0.01% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 490-505 (I
490
QEEKPKKKKKAQEDL
505
) of human ERp57.
SPECIFICITY:
Recognizes human ERp57. Detects a band of ~57kDa by Western blot.
APPLICATION:
Western Blot (1:500)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
Polyclonal Antibodies
ALX-210-406
Revised 19-Jan-05
Polyclonal Antibody to ERp72 (human)
SYNONYMS
anti-PDIA4 (human) PAb
anti-Protein Disulfide Isomerase A4 (human) PAb
PRODUCT LINE
Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY
Protein Synthesis, Modification & Degradation Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-406-C100
100 µg
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Epitope affinity purified antibody in PBS containing 1mg/ml BSA and 0.01% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 629-645 (K
629
FIEEHATKLSRTKEEL
645
) of human ERp72.
SPECIFICITY:
Recognizes human ERp72. Detects a band of ~72kDa by Western blot.
APPLICATION:
Western Blot (10µg/ml).
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
Polyclonal Antibodies
ALX-210-889
Revised 01-Nov-05
Polyclonal Antibody to PDIA6 (human)
SYNONYMS
anti-Protein Disulfide-isomerase A6 (human) PAb
anti-Protein Disulfide-isomerase P5 (human) PAb
PRODUCT LINE
Protein Synthesis, Modification & Degradation
PRODUCT CATEGORY
Protein Synthesis, Modification & Degradation Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-889-R100
100 µl
379.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Contains 0.01% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 476-492 (D
476
IDLSDVELDDLGKDEL
492
) of human PDIA6 (protein disulfide-isomerase A6; protein disulfide isomerase P5).
SPECIFICITY:
Recognizes human PDIA6. Detects a band of ~50kDa by Western blot.
APPLICATION:
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:
For Blocking Peptide see Prod. No.
ALX-165-068
.
Related Products
ALX-165-068
Blocking Peptide for PAb to PDIA6 (human) (Prod. No.
ALX-210-889
)
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
Polyclonal Antibodies
ALX-210-024
Revised 29-Jun-05
Polyclonal Antibody to TRAF2 (human) (Bur 34)
SYNONYMS
anti-Tumor Necrosis Factor (TNF) Receptor-associated Factor 2 (human) PAb (Bur 34)
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TRAFs / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-024-R050
50 µl
190.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. Antiserum containing PBS and 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 6-31(V
6
TPPGSLELLQPGFSKTLLGTKLEAK
31
) of human TRAF2 (tumor necrosis factor (TNF) receptor-associated factor 2).
SPECIFICITY:
Recognizes human TRAF2. Detects endogenous protein by IHC and WB. Detects a band of ~60-64kDa by Western blot. Does not cross-react with other members of the TRAF family.
APPLICATION:
Immunohistochemistry (paraffin sections (1:2'000)
Immunoprecipitation (1:50)
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -80°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies
:
J.M. Zapata, et al.; J. Immunol.
165
, 5084 (2000)
Abstract
;
Full Text
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
Polyclonal Antibodies
•
Autophagy Other Products
ALX-210-029
Revised 01-Jun-06
Polyclonal Antibody to TRAF2 (mouse) (AR-63)
SYNONYMS
anti-Tumor Necrosis Factor (TNF) Receptor-associated Factor 2 (mouse) PAb (AR-63)
PRODUCT LINE
Inflammation
PRODUCT CATEGORY
TRAFs / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-210-029-R050
50 µl
190.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST:
From rabbit.
FORMULATION:
Liquid. In PBS containing 0.05% sodium azide.
IMMUNOGEN:
Synthetic peptide corresponding to aa 250-271 (S
250
FLEAQASPG
TLNQVGPELLQR
271
) of mouse TRAF2 (tumor necrosis factor (TNF) receptor-associated factor 2).
SPECIFICITY:
Recognizes mouse TRAF2. Detects a band of ~60-64kDa by Western blot.
APPLICATION:
Immunoprecipitation (1:50)
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-80°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -80°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies
:
J.M. Zapata, et al.; J. Immunol.
165
, 5084 (2000)
Abstract
;
Full Text
General Information
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
Polyclonal Antibodies
•
Autophagy Other Products
ALX-270-428
Revised 25-Feb-08
Salubrinal
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
Phosphatases Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-270-428-M001
1 mg
30.00 USD
ALX-270-428-M005
5 mg
110.00 USD
Product Specification
FORMULA:
C
21
H
20
Cl
3
N
4
OS
MW:
479.8
CAS NUMBER:
405060-95-9
PURITY:
≥98%
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in DMSO (10mg/ml).
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Product may darken when exposed to air. Stock solutions are stable for up to 3 months when stored at -20°C.
HANDLING:
Protect from light. Keep under inert gas.
Product Description
Cell permeable and selective inhibitor of the phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Protects ER stress-induced apoptosis (EC
50
~15µM in PC12 cells stimulated with 750ng/ml of tunicamycin (Prod. No.
ALX-380-047
)).
Product Specific Literature References
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress:
M. Boyce, et al.; Science
307
, 935 (2005)
Abstract
A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death:
M. Boyce, et al.; Cell Death Differ.
15
, 589 (2008)
Abstract
Related Products
ALX-380-047
Tunicamycin
Further Categories Containing This Product:
Endoplasmatic Reticulum Stress
•
Translation Initiation Factors / Related Products
•
Apoptosis Inducers & Inhibitors Other Products
ALX-350-004
Revised 08-Apr-08
Thapsigargin
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Natural Products - Other Tumor Promoters
Ordering Information
