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Hydroxy, Hydroperoxy & Oxo Fatty Acids / Related Products
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ALX-340-037 Revised 08-Jul-08
8(S)-HETE
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SYNONYMS 8-Hydroxy-[S-(E,Z,Z,Z)]-5,9,11,14-eicosatetraenoic acid
PRODUCT LINE Oxidative Stress
PRODUCT CATEGORY Hydroxy, Hydroperoxy & Oxo Fatty Acids / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-340-037-C025   25 µg 165.00 USD Add To Cart
Product Specification
FORMULA: C20H32O3
MW: 320.5
CAS NUMBER: 98462-03-4
PURITY: ≥98%
FORMULATION: Liquid. Solution in ethanol.
SOLUBILITY: Soluble in DMSO or dimethyl formamide; slightly soluble in PBS, pH 7.2 (0.8mg/ml) or 0.1M Na2CO3 (2mg/ml)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 6 months in other organic solvents when stored at -20°C. Keep aqueous solutions on ice and use within 12 hours.
HANDLING: Protect from light and oxygen.

Product Description
Activator of PPARα. Activates mouse skin protein kinase C (PKC).
Product Specific Literature References
Investigation of the mechanism of biosynthesis of 8-hydroxyeicosatetraenoic acid in mouse skin: M.A. Hughes & A.R. Brash; Biochim. Biophys. Acta 1081, 347 (1991) Abstract
In vitro activation of mouse skin protein kinase C by fatty acids and their hydroxylated metabolites: H.H. Lo, et al.; Lipids 29, 547 (1994) Abstract
Differential activation of peroxisome proliferator-activated receptors by eicosanoids: K. Yu, et al.; J. Biol. Chem. 270, 23975 (1995) Abstract; Full Text
Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans: Y. Guan, et al.; Am. J. Physiol. 273, F1013 (1997) Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION To change the solvent, evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice.
Further Categories Containing This Product:
PPAR AgonistsPKC Activators
 
 

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