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Monocytes & Macrophages Other Products
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ALX-400-023 Revised 19-Apr-06
Gadolinium (III) chloride . hexahydrate
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PRODUCT LINE Immunology
PRODUCT CATEGORY Monocytes & Macrophages Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-400-023-M100   100 mg 15.00 USD Add To Cart
ALX-400-023-M500   500 mg 25.00 USD Add To Cart
Product Specification
FORMULA: GdCl3 . 6H2O
MW: 263.6 . 108.1
CAS NUMBER: 13450-84-5
MERCK INDEX: 14: 4326
PURITY: ≥99%
APPEARANCE: White crystals or chunks.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Packaged under inert gas. Hygroscopic.
HAZARD: IRRITANT.
Product Description
Inhibits macrophages.
Product Specific Literature References
Inhibition of macrophages with gadolinium chloride abrogates ozone- induced pulmonary injury and inflammatory mediator production: K.J. Pendino, et al.; Am. J. Respir. Cell Mol. Biol. 13, 125 (1995) Abstract
Further Categories Containing This Product:
Nitric Oxide Pathway Other Products
 
 
ALX-804-481 Revised 28-Apr-06
Monoclonal Antibody to Macrophage Marker (human) (3A5)
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PRODUCT LINE Immunology
PRODUCT CATEGORY Monocytes & Macrophages Other Products
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ALX-804-481-C125   125 µg 165.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 3A5
ISOTYPE: Mouse IgG2b
CONCENTRATION: ~250µg/ml
FORMULATION: Liquid. In serum free cell culture supernatant containing 0.7% BSA and 0.1% sodium azide.
IMMUNOGEN: Mouse popliteal lymphnode after subcutaneous immunisation in the footpad with fragments of human spleen depleted of lymphocytes and erythrocytes.
SPECIFICITY: Recognizes human macrophages and histiocytic cells in normal and diseased tissue. Does not stain dendritic cells (interdigitating cells, Langerhans' cells and microglia) nor myeloid, lymphoid or epithelial cells.
APPLICATION: Immunocytochemistry (1:20)
Immunohistochemistry (frozen sections, paraffin sections (1:20))
To improve staining results, preincubate formalin fixed sections with 10mM citrate buffer, pH 6.0, for 5 min. at 720 Watt in a microwave. Tissues fixed in sensofix and sublimate buffer formalin do not need pretreatment.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
Product Specific Literature References
A new monoclonal antibody (3A5) that recognises a fixative resistant epitope on tissue macrophages and monocytes: E.H. Jaspars, et al.; J. Clin. Pathol. 47, 248 (1994) Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
 
 
ALX-804-661 Revised 13-Mar-08
Monoclonal Antibody to CLEC12B (human) (16)
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SYNONYMS anti-C-type Lectin Domain Family 12 Member B (human) MAb (16)
PRODUCT LINE Immunology
PRODUCT CATEGORY Monocytes & Macrophages Other Products
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ALX-804-661-C100   100 µg 260.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE: 16
ISOTYPE: Mouse IgG2a
CONCENTRATION: 1mg/ml
FORMULATION: Liquid. In PBS, pH 7.4, containing 50% glycerol.
IMMUNOGEN: Ba/F3 cells transfected with human CLEC12B.
SPECIFICITY: Recognizes human CLEC12B.
APPLICATION: ELISA (1µg/ml)
Flow Cytometry (10µg/ml)
Western Blot (1µg/ml)
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least one year after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles.
Product Images
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Product Specific Literature References
Identification of CLEC12B, an Inhibitory Receptor on Myeloid Cells: S.C. Hoffmann, et al.; J. Biol. Chem. 282, 22370 (2007) Abstract
Further Categories Containing This Product:
Immune Receptors Other Products • Monoclonal Antibodies
 
 
ALX-804-809 Revised 24-Mar-05
Monoclonal Antibody to MFG-E8 (mouse) (2422)
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SYNONYMS anti-Milk Fat Globule-EGF Factor 8 (mouse) MAb (2422)
anti-MFGM (mouse) MAb (2422)
anti-Sperm Surface Protein SP47 (mouse) MAb (2422)
anti-MP47 (mouse) MAb (2422)
anti-Lactadherin [Precursor] (mouse) MAb (2422)
PRODUCT LINE Immunology
PRODUCT CATEGORY Monocytes & Macrophages Other Products
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ALX-804-809-C100   100 µg 360.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
CLONE: 2422
ISOTYPE: Hamster Ig
CONCENTRATION: 1mg/ml.
PURITY: ≥95% (SDS-PAGE)
FORMULATION: Liquid. Purified antibody in PBS containing 0.02% sodium azide.
IMMUNOGEN: Thioglycollate-elicited mouse peritoneal macrophages.
SPECIFICITY: Recognizes mouse MFG-E8.
APPLICATION: Flow Cytometry
Immunoprecipitation
Functional Application (agonistic; increases uptake of apoptotic cells by macrophages and enhances internalization of exosomes by dendritic cells)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Identification of a factor that links apoptotic cells to phagocytes: R. Hanayama, et al.; Nature 417, 182 (2002) Abstract
Cell biology. Tickling macrophages, a serious business.: S. Zullig & M.O. Hengartner; Science 304, 1123 (2004) Abstract
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice.: R. Hanayama, et al.; Science 304, 1147 (2004) Abstract
Expression of developmental endothelial locus-1 in a subset of macrophages for engulfment of apoptotic cells.: R. Hanayama, et al.; J. Immunol. 172, 3876 (2004) Abstract
General Information
MANUFACTURER Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Autoimmunity & Self Tolerance Other Products • Monoclonal Antibodies • Cell Death / Apoptosis / Autophagy Other Products
 
 
ALX-210-272 Revised 08-Jul-05
Polyclonal Antibody to EMAPII (human)
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SYNONYMS anti-Endothelial Monocyte-activating Polypeptide II (human) PAb
PRODUCT LINE Immunology
PRODUCT CATEGORY Monocytes & Macrophages Other Products
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ALX-210-272-C100   100 µg 259.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. In PBS.
IMMUNOGEN: Recombinant human EMAPII (endothelial monocyte-activating polypeptide II).
SPECIFICITY: Recognizes human EMAPII.
APPLICATION: ELISA
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
ALX-210-273 Revised 08-Jul-05
Polyclonal Antibody to EMAPII (mouse)
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SYNONYMS anti-Endothelial Monocyte-activating Polypeptide II (mouse) PAb
PRODUCT LINE Immunology
PRODUCT CATEGORY Monocytes & Macrophages Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-273-C100   100 µg 259.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. In PBS.
IMMUNOGEN: Recombinant mouse EMAPII (endothelial monocyte-activating polypeptide II).
SPECIFICITY: Recognizes mouse EMAPII.
APPLICATION: ELISA
Western Blot
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
Further Categories Containing This Product:
Polyclonal Antibodies
 
 
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