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ALX-804-345
Revised 07-Feb-06
Monoclonal Antibody to Procathepsin W (human) (CW 40-1B1)
SYNONYMS
anti-Lymphopain Precursor (human) MAb (CW 40-1B1)
anti-Cathepsin W Precursor (human) MAb (CW 40-1B1)
PRODUCT LINE
Cancer
PRODUCT CATEGORY
Cathepsin Antibodies
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-804-345-C200
200 µg
460.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
CW 40-1B1
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Protein G purified antibody in PBS containing 0.01%thimerosal.
IMMUNOGEN:
Purified recombinant human procathepsin W.
SPECIFICITY:
Recognizes the epitope E
76
EFGQLY
82
of human procathepsin W. Does not cross-react with mature cathepsins B, D, H, K, L, S, W or procathepsins B, F, L, S.
APPLICATION:
Flow Cytometry
Immunohistochemistry
Western Blot
Optimal conditions must be determined individually for each application. Dilutions given in the figures below may be used as guidelines.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
+4°C
HANDLING:
Do not freeze.
Product Images
Please click on thumbnails to enlarge.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-489
Revised 02-Jun-05
Monoclonal Antibody to CCL1 (human) (8P16-N4-L21)
SYNONYMS
anti-I-309 (human) MAb (8P16-N4-L21)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-489-C100
100 µg
220.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
8P16-N4-L21
ISOTYPE:
Mouse IgM
CONCENTRATION:
1mg/ml
PURITY DETAIL:
DEAE purified.
FORMULATION:
Liquid. In PBS.
IMMUNOGEN:
Recombinant human CCL1 (I-309).
SPECIFICITY:
Recognizes human CCL1.
APPLICATION:
Immunohistochemistry (frozen sections (5µg/ml))
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-594
Revised 10-Jun-05
Monoclonal Antibody to CCL2 (human) (5J.1)
SYNONYMS
anti-MCP-1 (human) MAb (5J.1)
anti-Monocyte Chemotactic Protein-1 (human) MAb (5J.1)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-594-C100
100 µg
220.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
5J.1
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS.
IMMUNOGEN:
Recombinant human CCL2 (monocyte chemotactic protein-1; MCP-1).
SPECIFICITY:
Recognizes human CCL2.
APPLICATION:
Immunohistochemistry (frozen sections (5µg/ml))
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-465
Revised 29-Feb-08
Monoclonal Antibody to CCL2 (human) (5D3-F7)
SYNONYMS
anti-MCP-1 (human) MAb (5D3-F7)
anti-Monocyte Chemotactic Protein-1 (human) MAb (5D3-F7)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-804-465-C100
100 µg
350.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
5D3-F7
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Purified antibody in PBS containing 0.1% sodium azide.
IMMUNOGEN:
Recombinant human CCL2 (monocyte chemotactic protein-1; MCP-1).
SPECIFICITY:
Recognizes human CCL2.
APPLICATION:
ELISA (capture)
Immunocytochemistry (1:1'000)
Immunohistochemistry (frozen sections, paraffin sections (1:250-1:500))
Immunoprecipitation
Western Blot (1:1'000)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
A new monoclonal antibody (5D3-F7) which recognizes human monocyte chemotactic protein-1 but not related chemokines. Development of a sandwich ELISA and in situ detection of producing cells
:
G. Peri, et al.; J. Immunol. Methods
174
, 249 (1994)
Abstract
Analysis of the Gene Expression Profile Activated by the CC Chemokine Ligand 5/RANTES and by Lipopolysaccharide in Human Monocytes:
M. Locati, et al.; J. Immunol.
168
, 3557 (2002)
Full Text
Human Pancreatic Islets Produce and Secrete MCP-1/CCL2: Relevance in Human Islet Transplantation:
L. Piemonti, et al.; Diabetes
51
, 55 (2002)
Full Text
Further Categories Containing This Product:
Osteocalcin & Matrix Gla-protein [MGP] Family / Related Products
•
Monoclonal Antibodies
ALX-804-549
Revised 29-Feb-08
Monoclonal Antibody to CCL2 (human) (D9)
SYNONYMS
anti-MCP-1 (human) MAb (D9)
anti-Monocyte Chemotactic Protein-1 (human) MAb (D9)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
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Unit Price:
Quantity:
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ALX-804-549-C100
100 µg
220.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
D9
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. Protein G purified antibody in PBS.
IMMUNOGEN:
Recombinant human CCL2 (monocyte chemotactic protein-1; MCP-1).
SPECIFICITY:
Recognizes human CCL2.
APPLICATION:
Immunoprecipitation
Western Blot (5µg/ml)
Functional Application (blocks CCL2 [MCP-1]; 2µg/ml)
Not recommended for immunohistochemistry.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-470
Revised 10-May-06
Monoclonal Antibody to CCL22 (human) (152/11)
SYNONYMS
anti-MDC (human) MAb (152/11)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-470-C250
250 µg
540.00 USD
ALX-804-470E-C250
Peroxidase
250 µg
580.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
152/11
ISOTYPE:
Rat IgG
CONCENTRATION:
ALX-804-470
: 2.3mg/ml
ALX-804-470E
: 0.36mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
ALX-804-470
: Liquid. In PBS, pH 7.4.
ALX-804-470E
: Liquid. In PBS, pH 7.4, containing 0.2% bronidox and 0.05% phenol.
IMMUNOGEN:
Recombinant human CCL22 (macrophage-derived chemokine; MDC).
SPECIFICITY:
Recognizes human CCL22.
APPLICATION:
ALX-804-470
: Western Blot (2-4µg/ml)
Detection Limit: 0.2µg/lane.
ALX-804-470E
: ELISA (detection (1-2µ/ml))
Use microtiter plates coated with primary antibody (Prod. No.
ALX-804-469
, MAb to CCL22 (human) (349/6) at 20µg/ml in 0.05M carbonate/bicarbonate buffer, pH 9.6) to detect human fractalkine.
Detection Limit: ~60pg/ml.
Substrate: 0.26mg/ml tetramethyl benzydine and 0.01% hydrogen peroxide stabilized in 0.05M citrate buffer, pH 3.8.
SHIPPING:
SHIPPED ON BLUE ICE
USE/STABILITY:
ALX-804-470
: Short Term Storage: +4°C. Long Term Storage: After opening, prepare aliquots and store at -20°C.
ALX-804-470E
: Long Term Storage: +4°C.
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-469
Revised 07-May-08
Monoclonal Antibody to CCL22 (human) (349/6)
SYNONYMS
anti-MDC (human) MAb (349/6)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-804-469-C250
250 µg
540.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
349/6
ISOTYPE:
Rat IgG
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:
Recombinant human CCL22 (macrophage-derived chemokine; MDC).
SPECIFICITY:
Recognizes human CCL22.
APPLICATION:
ELISA
(capture (20µg/ml))
Use microtiter plates coated with this antibody in 0.05M carbonate/bicarbonate buffer, pH 9.6, in combination with secondary antibody (Prod. No.
ALX-804-470
, MAb to CCL22 (human) (152/11)) at 1-2µg/ml to detect human MDC.
Detection Limit: ~40pg/ml.
Substrate: 0.26mg/ml tetramethyl benzydine and 0.01% hydrogen peroxide stabilized in 0.05M citrate buffer, pH 3.8.
Western Blot
(1-2µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Preservative may be added for storage at +4°C.
HANDLING:
For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-804-591
Revised 20-Nov-06
Monoclonal Antibody to CCR3 (human) (5E8)
SYNONYMS
anti-C-C Chemokine Receptor 3 (human) MAb (5E8)
anti-Eotaxin Receptor (human) MAb (5E8)
PRODUCT LINE
Chemokines & Cytokines
PRODUCT CATEGORY
CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
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ALX-804-591-C100
100 µg
220.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
5E8
ISOTYPE:
Mouse IgG2a
CONCENTRATION:
1mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS.
IMMUNOGEN:
L1.2 cells expressing human CCR3 (C-C Chemokine Receptor 3).
SPECIFICITY:
Recognizes human CCR3.
APPLICATION:
Flow Cytometry
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Further Categories Containing This Product:
Monoclonal Antibodies
ALX-805-058
Revised 11-Apr-05
Monoclonal Antibody to CD2 (human) (MEM-65)
SYNONYMS
anti-LFA-2 (human) MAb (MEM-65)
anti-T11 (human) MAb (MEM-65)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD2 [LFA-2] & CD58 [LFA-3] / Related Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
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ALX-805-058-C100
100 µg
195.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MEM-65
ISOTYPE:
Mouse IgG1
CONCENTRATION:
1mg/ml
FORMULATION:
Liquid. In PBS, pH 7.4, containing 0.1% sodium azide.
IMMUNOGEN:
Human peripheral T cells.
SPECIFICITY:
Recognizes a unique epitope of human CD2 (LFA-2) implicated in T cell activation.
APPLICATION:
Flow Cytometry
Immunoprecipitation
Western Blot
Functional Application (studying CD2 ligand-binding mechanisms involved with T cell development and activation)
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stable for 6 months when stored at +4°C.
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
New monoclonal antibodies to human leucocyte surface molecule CD2:
K. Drbal, et al.; Folia Biol.
43
, 245 (1997)
Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-805-057
Revised 05-Sep-06
Monoclonal Antibody to CD3 (human) (MEM-57)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD3 - Marker for T Cells
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-805-057-C100
100 µg
195.00 USD
ALX-805-057F-T100
FITC
100 tests
270.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
MEM-57
ISOTYPE:
Mouse IgG2a
CONCENTRATION:
MEM-57
: 1mg/ml.
PURITY DETAIL:
Protein A-affinity purified.
FORMULATION:
MEM-57
: Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
MEM-57-FITC
: Liquid. In PBS, pH 7.4, containing 15mM sodium azide and 0.2% BSA.
IMMUNOGEN:
Human thymocytes and T lymphocytes.
SPECIFICITY:
Recognizes the ε and δ chain of human CD3.
APPLICATION:
Flow Cytometry (20µl per 100µ of whole blood or 10
6
cells in suspension)
Immunoprecipitation
Functional Application (activates T cells
in vitro
; highly effective immunosuppressive agent)
SHIPPING:
SHIPPED ON BLUE ICE
USE/STABILITY:
MEM-57
: Short Term Storage: +4°C. Stable for 6 months.
Long Term Storage: -20°C. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
MEM-57-FITC
: Store at +4°C. Do not freeze! Protect from light!
Product Specific Literature References
Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74):
V. Horejsi, et al.; Folia Biol. (Praha)
34
, 23 (1988)
Abstract
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-804-822
Revised 18-Aug-08
Monoclonal Antibody to CD3 (human) (TR66)
SYNONYMS
anti-CD3 (human) MAb (TR66)
PRODUCT LINE
Immunology
PRODUCT CATEGORY
CD3 - Marker for T Cells
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-804-822-C100
100 µg
190.00 USD
ALX-804-822TD-T100
ATTO 488
100 tests
250.00 USD
ALX-804-822TS-T100
ATTO 647N
100 tests
250.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
CLONE:
TR66
ISOTYPE:
Mouse IgG1
SOURCE/HOST:
Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:
1mg/ml
PURITY:
>95% (SDS-PAGE).
FORMULATION:
Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:
Cloned human helper T cell line.
SPECIFICITY:
Recognizes the ε-chain of human CD3. Detects endogenous protein by FC, ICC and IP.
APPLICATION:
Flow Cytometry
Immunocytochemistry
Immunoprecipitation
Functional Application: T cell stimulation
SHIPPING:
SHIPPED ON BLUE ICE
SHORT TERM STORAGE:
+4°C
USE/STABILITY:
Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:
For long term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Keep conjugated formats at +4°C. Do not freeze. Protect from light.
Product Specific Literature References
The use of hybrid hybridomas to target human cytotoxic T lymphocytes
:
A. Lanzavecchia & D. Scheidegger; Eur. J. Immunol.
17
, 105 (1987)
Abstract
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation
:
T. Kataoka, et al.; J. Immunol.
161
, 3936 (1998)
Abstract
;
Full Text
T lymphocyte costimulation mediated by reorganization of membrane microdomains
:
A. Viola, et al.; Science
283
, 680 (1999)
Abstract
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation
:
O. Gaide, et al.; Nat. Immunol.
3
, 836 (2002)
Abstract
T cell fitness determined by signal strength
:
A.V. Gett, et al.; Nat. Immunol.
4
, 355 (2003)
Abstract
General Information
BACKGROUND/TECHNICAL INFORMATION
1 test means: 1µl of MAb is used to stain 500’000 cells in a sample volume of 50µl.
MANUFACTURER
Manufactured by Apotech Corporation.
Further Categories Containing This Product:
Monoclonal Antibodies
•
CD Antibodies
ALX-805-053
Revised 05-Oct-06
Monoclonal Antibody to CD4 (human) (MEM-115)
