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Anthocyanidins
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ALX-385-003 Revised 03-Apr-08
Cyanidin chloride
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SYNONYMS 3,3',4',5,7-Pentahydroxy-flavylium chloride
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Anthocyanidins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-385-003-M010   10 mg 195.00 USD Add To Cart
ALX-385-003-M050   50 mg 780.00 USD Add To Cart
Product Specification
FORMULA: C15H11ClO6
MW: 322.7
CAS NUMBER: 528-58-5
MERCK INDEX: 14: 2687
RTECS: LK9824000
PURITY: ≥97%
APPEARANCE: Dark red to black solid.
SOLUBILITY: Soluble in methanol or 0.1% hydrochloric acid.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
IDENTITY: Identity determined by 1H-NMR, 13C-NMR and MS.

Product Description
Antioxidant flavonoid. Nitric oxide (NO) scavenger.
Product Specific Literature References
Flavonoids as scavengers of nitric oxide radical: S.A.B.E. Acker, et al.; BBRC 214, 755 (1995) Abstract
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radical Biol. & Med. 20, 933 (1996), (Review) Abstract
Dietary flavonoids: bioavailability, metabolic effects, and safety: J.A. Ross & C.M. Kasum; Annu. Rev. Nutr. 22, 19 (2002), (Review) Abstract
Cyanidins: metabolism and biological properties: F. Galvano, et al.; J. Nutr. Biochem. 15, 2 (2004), (Review) Abstract
 
 
ALX-385-028 Revised 03-Apr-08
Delphinidin chloride (high purity)
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Anthocyanidins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-385-028-M010   10 mg 460.00 USD Add To Cart
Product Specification
FORMULA: C15H11ClO7
MW: 338.7
CAS NUMBER: 528-53-0
RTECS: DK1310000
PURITY: ≥97% (HPLC)
APPEARANCE: Red to dark brown powder.
SOLUBILITY: Soluble in water or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light and moisture.

Product Description

Anthocyanidin with antioxidant effect found in pigmented fruits and vegetables. Shown to inhibit angiogenesis and endothelial cell apoptosis by stimulating nitric oxide (NO) production. Inhibits solar radiation (UVB)-mediated oxidative stress, reducing DNA damage.

Product Specific Literature References
Delphinidin, an active compound of red wine, inhibits endothelial cell apoptosis via nitric oxide pathway and regulation of calcium homeostasis: S. Martin, et al.; Br. J. Pharmacol. 139, 1095 (2003) Abstract; Full Text
Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines: M.C. Lazzè; Carcinogenesis 25, 1427 (2004) Abstract; Full Text
DNA interaction with naturally occurring antioxidant flavonoids quercetin, kaempferol, and delphinidin: C.D. Kanakis, et al.; J. Biomol. Struct. Dyn. 22, 719 (2005) Abstract
Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK: M.H. Oak, et al.; Br. J. Pharmacol. 149, 283 (2006) Abstract; Full Text
Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation: S. Lamy, et al.; Carcinogenesis 27, 989 (2006) Abstract; Full Text
Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis: F. Afaq, et al.; J. Invest. Dermatol. 127, 222 (2007) Abstract; Full Text
 
 
ALX-385-013 Revised 16-Jun-08
Malvidin chloride
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SYNONYMS 3,4',5,7-Tetrahydroxy-3',5'-dimethoxyflavylium chloride
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Anthocyanidins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-385-013-M010   10 mg 260.00 USD Add To Cart
Product Specification
FORMULA: C17H15O7Cl
MW: 366.8
CAS NUMBER: 643-84-5
MERCK INDEX: 14: 5715
RTECS: LK9900000
PURITY: ≥97%
APPEARANCE: Reddish brown to black powder.
SOLUBILITY: Soluble in 100% ethanol; slightly soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Protect from light. Hygroscopic.

Product Description
Antioxidant flavonoid. Antitumor compound. Induces cell cycle arrest in the G2/M-phase.
Product Specific Literature References
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radical Biol. & Med. 20, 933 (1996), (Review) Abstract
Biological activities of malvidin, a red wine anthocyanidin: J. Fritz, et al.; Mol. Nutr. Food Res. 50, 390 (2006) Abstract
 
 
ALX-385-014 Revised 19-Nov-07
Pelargonidin chloride
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PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Anthocyanidins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-385-014-M005   5 mg 135.00 USD Add To Cart
Product Specification
FORMULA: C15H11O5Cl
MW: 306.7
CAS NUMBER: 134-04-3
MERCK INDEX: 14: 7071
PURITY: ≥97% (HPLC)
APPEARANCE: Red to brown solid.
SOLUBILITY: Soluble in 100% ethanol or methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C

Product Description
Antioxidant flavonoid. Nitric oxide scavenger.
Product Specific Literature References
Flavonoids as scavengers of nitric oxide radical: S.A.B.E. Acker, et al.; BBRC 214, 755 (1995) Abstract
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radical Biol. & Med. 20, 933 (1996), (Review) Abstract
Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin: Y. Noda, et al.; J. Agric. Food Chem. 50, 166 (2002) Abstract
Antigenotoxic effects of the phytoestrogen pelargonidin chloride and the polyphenol chlorogenic acid: S.K. Abraham, et al.; Mol. Nutr. Food Res. 51, 880 (2007) Abstract
 
 
ALX-385-015 Revised 12-Aug-08
Peonidin chloride
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SYNONYMS 3,4',5,7-Tetrahydroxy-3'-methoxyflavylium chloride
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Anthocyanidins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-385-015-M005   5 mg 280.00 USD Add To Cart
Product Specification
FORMULA: C16H13O6Cl
MW: 336.7
CAS NUMBER: 134-01-0
MERCK INDEX: 14: 7143
PURITY: ≥99% (HPLC)
APPEARANCE: Beige to reddish-brown solid.
SOLUBILITY: Soluble in 100% ethanol or water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C
HANDLING: Protect from light.

Product Description
Antioxidant flavonoid. Shows anti-inflammatory and chemopreventive properties.
Product Specific Literature References
Structure-antioxidant activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radical Biol. & Med. 20, 933 (1996), (Review) Abstract
Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2: J.Y. Kwon, et al.; Ann. N. Y. Acad. Sci. 1095, 513 (2007) Abstract
 
 

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