ALEXIS Biochemicals: PAC-1

ALX-430-146

Revised 30-Nov-06

PAC-1
SYNONYMS	4-(Phenylmethyl)[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide-1-piperazine acetic acid
PRODUCT LINE	Cancer
PRODUCT CATEGORY	Antitumor Agents (Apoptosis Inducers)

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-146-M010		10 mg	45.00 USD
ALX-430-146-M050		50 mg	180.00 USD

Product Specification

FORMULA:	C₂₃H₂₈N₄O₂
MW:	392.5
CAS NUMBER:	315183-21-2
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in acetonitrile, DMSO, dioxane or methanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

First molecule to directly activate procaspase-3 to caspase-3 in vitro. Has been shown to induce apoptosis in cancer cells.

Product Specific Literature References

Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy: K.S. Putt, et al.; Nat. Chem. Biol. 2, 543 (2006) Abstract

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