ALEXIS Biochemicals: PDGF β-Receptor (719-723) (phosphorylated)

ALX-165-005

Revised 16-Feb-05

PDGF β-Receptor (719-723) (phosphorylated)
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	SH2 & SH3 Domains

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-165-005-M001		1 mg	130.00 USD
ALX-165-005-M005		5 mg	520.00 USD

Product Specification

SEQUENCE:	H-Tyr(PO₃H₂)-Val-Pro-Met-Leu-OH
FORMULA:	C₃₀H₄₈N₅O₁₀PS
MW:	701.8
PURITY:	≥97%
APPEARANCE:	White lyophilized powder.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Contains the PDGF β-receptor recognition sequence which specifically interacts with the SH2 domain of PI(3)K (phosphoinositide 3-kinase). In this phosphorylated form the peptide inhibits the binding of the 85kDa subunit of PI(3)K to the PDGF β-receptor.

Product Specific Literature References

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways: W.J. Fantl, et al.; Cell 69, 413 (1992) Abstract
Closing in on SH2 specificity: R.B. Birge & H. Hanafusa; Science 262, 1522 (1993) Abstract

Further Categories Containing This Product:

Peptides • Platelet-derived Growth Factors [PDGFs] & Receptors / Related Products

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