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ALX-550-347 Revised 29-Jan-05
PPADS . tetrasodium salt
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SYNONYMS Pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid . 4Na
PRODUCT LINE Neurobiology
PRODUCT CATEGORY P2X Purinergic Receptors/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-550-347-M010   10 mg 40.00 USD Add To Cart
Product Specification
FORMULA: C14H10N3O12PS2 . 4Na
MW: 507.3 . 92.0
CAS NUMBER: 192575-19-2
PURITY: ≥98%
APPEARANCE: Orange solid.
SOLUBILITY: Soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light. Hygroscopic.

Product Description
Selective P2 purinoceptor antagonist which blocks responses at both pre- and postjunctional sites.
Product Specific Literature References
PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses: G. Lambrecht, et al.; Eur. J. Pharmacol. 217, 217 (1992) Abstract
PPADS selectively antagonizes P2X-purinoceptor-mediated responses in the rabbit urinary bladder: A.U. Ziganshin, et al.; Br. J. Pharmacol. 110, 1491 (1993) Abstract
Investigation of the actions of PPADS, a novel P2X-purinoceptor antagonist, in the guinea-pig isolated vas deferens: G.J. MacLaren, et al.; Br. J. Pharmacol. 111, 913 (1994) Abstract
Selective antagonism by PPADS at P2X-purinoreceptors in rabbit isolated blood vessels: A.U. Ziganshin, et al.; Br. J. Pharmacol. 111, 923 (1994) Abstract
PPADS: an antagonist at the endothelial P2Y-purinoceptors but not P2U-purinoceptors: C. Brown, et al.; Br. J. Pharmacol. 116, 2413 (1995) Abstract
PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors: S.J. Charlton, et al.; Br. J. Pharmacol 118, 704 (1996) Abstract
Hydrolysis of P2-purinoceptor agonists by a purified ectonucleotidase from the bovine aorta, the ATP-diphosphohydrolase: M. Picher, et al.; Biochem. Pharmacol. 51, 1453 (1996) Abstract
Discrimination by PPADS between endothelial P2Y- and P2U-purinoceptors in the rat isolated mesenteric arterial bed: V. Ralevic & G. Burnstock; Br. J. Pharmacol. 118, 428 (1996) Abstract
 
 
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