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ALX-340-019 Revised 08-Jul-08
Palmityl trifluoromethylketone
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SYNONYMS PACOCF3
PTK
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY PLA2 Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-340-019-M010   10 mg 109.00 USD Add To Cart
Product Specification
FORMULA: C17H31F3O
MW: 308.4
CAS NUMBER: 141022-99-3
PURITY: ≥98%
FORMULATION: Liquid. Solution in ethanol.
SOLUBILITY: 30mg/ml soluble in DMSO or dimethyl formamide; sparingly soluble in neutral buffers.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 2 years after receipt when stored at -20C°. Not stable in basic solutions (pH > 7.4). We do not recommend storing aqueous solutions for more than one day.

Product Description
Inhibitor of both Ca2+-dependent cytosolic and Ca2+-independent phospholipases A2 (PLA2).
Product Specific Literature References
Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones: E.J. Ackermann, et al.; J. Biol. Chem. 270, 445 (1995) Abstract; Full Text
Activated ketones as inhibitors of intracellular Ca2+-dependent and Ca2+-independent phospholipase A: K. Conde-Friesboes, et al.; JACS 118, 5519 (1996)
General Information
BACKGROUND/TECHNICAL INFORMATION To change the solvent, evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice.
 
 

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