ALEXIS Biochemicals: Papuamine

ALX-350-348

Revised 22-Feb-08

Papuamine
SYNONYMS	(-)-Papuamine
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Antifungal Agents

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-348-M001		1 mg	160.00 USD

Product Specification

FORMULA:	C₂₅H₄₀N₂
MW:	368.6
CAS NUMBER:	112455-84-2
SOURCE/HOST:	Isolated from sponge Haliclona sp.
PURITY:	≥97% (HPLC)
APPEARANCE:	Yellow amorphous solid.
SOLUBILITY:	Soluble in DMSO, methanol or 100% ethanol; poorly soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light and moisture.
IDENTITY:	Determined by ¹H-NMR, ¹³C-NMR and MS.

Product Description

C₂-symmetrical pentacyclic alkaloid with antifungal and antimycobacterial activity.

Product Specific Literature References

Papuamine, an antifungal pentacyclic alkaloid from a marine sponge Haliclona sp.: B.J. Baker, et al.; JACS 110, 965 (1988)
Total Synthesis of (+)-Papuamine: An Antifungal Pentacyclic Alkaloid from a Marine Sponge, Haliclona sp.: A.G.M. Barrett, et al.; J. Org. Chem. 61, 685 (1996) Abstract
Total Syntheses of (-)-Papuamine and (-)-Haliclonadiamine: T.S McDermott, et al.; J. Org. Chem. 61, 700 (1996) Abstract
Towards a Biomimetic Synthesis of the Marine Alkaloids Papuamine and Haliclonadiamine: Model Studies: R.M. Adlington, et al. ; Tetrahedron 56, 623 (2000)
A Mycobacterium marinum zone of inhibition assay as a method for screening potential antimycobacterial compounds from marine extracts: L.P. Barker, et al.; Planta Med. 73, 559 (2007) Abstract

Further Categories Containing This Product:

Natural Products - Other Anti-infective Agents

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