ALEXIS Biochemicals: Paraherquamide A

ALX-380-215

Revised 08-Apr-08

Paraherquamide A
SYNONYMS	VM 29919
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-215-M001		1 mg	390.00 USD

Product Specification

FORMULA:	C₂₈H₃₅N₃O₅
MW:	493.6
CAS NUMBER:	77392-58-6
RTECS:	RV0545000
SOURCE/HOST:	Isolated from Penicillium simplicissimum MST-FP116A.
PURITY:	≥95% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	TOXIC.

Product Description

Antibiotic. Selective and competitive cholinergic antagonist that distinguishes subtypes of cholinergic receptors. Anti-helmintic.

Product Specific Literature References

Novel antinematodal and antiparasitic agents from Penicillium charlesii. I. Fermentation, isolation and biological activity: J.G. Ondeyka, et al.; J. Antibiot. (Tokyo) 43, 1375 (1990) Abstract
Acute toxicity of paraherquamide and its potential as an anthelmintic: W.L. Shoop, et al.; Am. J. Vet. Res. 53, 2032 (1992) Abstract
Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals: E.W. Zinser, et al.; J. Vet. Pharmacol. Ther. 25, 241 (2002) Abstract
Paraherquamide and 2-deoxy-paraherquamide distinguish cholinergic receptor subtypes in Ascaris muscle: A.P. Robertson, et al.; J. Pharmacol. Exp. Ther. 302, 853 (2002) Abstract; Full Text

Further Categories Containing This Product:

Helminth Infections / Related Products • Acetylcholine Receptors Other Products

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