ALEXIS Biochemicals: Pectenotoxin-2

ALX-350-369

Revised 08-Apr-08

Pectenotoxin-2
SYNONYMS	4,3-Dioxypectenotoxin
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Other Toxins

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-369-C005		5 µg	360.00 USD

Product Specification

FORMULA:	C₄₇H₇₀O₁₄
MW:	859.1
CAS NUMBER:	97564-91-5
SOURCE/HOST:	Isolated from Dinophysis acuta.
CONCENTRATION:	10µg/ml
PURITY:	≥95%
FORMULATION:	Liquid. In methanol.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HAZARD:	VERY TOXIC.

Product Description

Potent disruptor of actin cytoskeleton in living cells. Forms 1:1 complexes with monomeric actin and caps actin filaments. Selective cytotoxic agent against several human cancer cell lines. Hepatotoxic.

Product Specific Literature References

Cytotoxic compounds from a two-sponge association: J.H. Jung, et al.; J. Nat. Prod. 58, 1722 (1995) Abstract
New anti-actin drugs in the study of the organization and function of the actin cytoskeleton: I. Spector, et al.; Microsc. Res. Tech. 47, 18 (1999) Abstract
Oocyte-based screening of cytokinesis inhibitors and identification of pectenotoxin-2 that induces Bim/Bax-mediated apoptosis in p53-deficient tumors: H.D. Chae, et al.; Oncogene 24, 4813 (2005) Abstract
A structural basis for regulation of actin polymerization by pectenotoxins: J.S. Allingham, et al.; J. Mol. Biol. 371, 959 (2007) Abstract

Further Categories Containing This Product:

Natural Products for Cytoskeletal Research • Natural Products - Antitumor Reagents

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.