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ALX-400-036 Revised 31-Oct-06
Peroxynitrite . tetramethylammonium
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SYNONYMS ONOO- . C4H12N
Oxoperoxonitrate(1-) . C4H12N
PRODUCT LINE Oxidative Stress
PRODUCT CATEGORY Peroxynitrite/Scavengers/Detection
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-400-036-L001   1 ml 152.00 USD Add To Cart
ALX-400-036-5001   5x1 ml 475.00 USD Add To Cart
Product Specification
FORMULA: NO3 . C4H12N
MW: 62.0 . 74.1
CAS NUMBER: 14042-01-4
CONCENTRATION: ~10mM
FORMULATION: Liquid. In 0.01M KOH.
SHIPPING: SHIPPED ON DRY ICE
LONG TERM STORAGE: -80°C
USE/STABILITY: Stable for at least 1 month after receipt when stored at -80°C.
HANDLING: Protect from light.
HAZARD: OXIDIZING. CORROSIVE.

Product Description
Produced from the reaction of nitrogen monoxide with tetramethylammonium superoxide according to the method of D.S. Bohle, et al. described in Meth. Enzymol. 269, 302 (1996), and dissolved in 0.01M potassium hydroxide (KOH). This formulation of peroxynitrite has a low nitrite content (~1%), no hydrogen peroxide.
Product Specific Literature References
DNA damage induced by peroxynitrite: subsequent biological effects: C. Szabo & H. Ohshima; Nitric Oxide 1, 373 (1997), (Review) Abstract
Peroxynitrite: a biologically significant oxidant: M.P. Murphy, et al.; Gen. Pharmacol. 31, 179 (1998), (Review) Abstract
Peroxynitrite: an endogenous oxidizing and nitrating agent: C. Ducrocq, et al.; Cell. Mol. Life Sci. 55, 1068 (1999), (Review) Abstract
The chemistry of DNA damage from nitric oxide and peroxynitrite: S. Burney, et al.; Mutat. Res. 424, 37 (1999), (Review) Abstract
Reactions of *NO, *NO2 and peroxynitrite in membranes: physiological implications: S.P. Goss, et al.; Free Radic. Res. 31, 597 (1999), (Review) Abstract
Peroxynitrite: reactive, invasive and enigmatic: J.T. Groves; Curr. Opin. Chem. Biol. 3, 226 (1999), (Review) Abstract
Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good: a personal view of recent controversies: B. Halliwell, et al.; Free Radic. Res. 31, 651 (1999), (Review) Abstract
Assessment of peroxynitrite scavengers in vitro: B. Halliwell, et al.; Meth. Enzymol. 301, 333 (1999), (Review) Abstract
Chemistry of peroxynitrite and its relevance to biological systems: W.H. Koppenol; Met. Ions Biol. Syst. 36, 597 (1999), (Review) Abstract
Conformation of peroxynitrite: determination by crystallographic analysis: M. Worle, et al.; Chem. Res. Toxicol 12, 305 (1999) Abstract
Peroxynitrite scavenging by metalloporphyrins and thiolates: J.P. Crow; Free Radic. Biol. Med. 28, 1487 (2000), (Review) Abstract
Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics: H. Sies & G.E. Arteel; Free Radic. Biol. Med. 28, 1451 (2000), (Review) Abstract
Reactions of Peroxynitrite with Phenolic and Carbonyl Compounds: Flavonoids are not Scavengers of Peroxynitrite: S. Tibi & W.H. Koppenol; Helv. Chim. Acta 83, 2412 (2000)
BCL-2 protects peroxynitrite-treated thymocytes from poly(ADP-ribose) synthase (PARS)-independent apoptotic but not from PARS-mediated necrotic cell death: L. Virag & C. Szabo; Free Radic. Biol. Med. 29, 704 (2000) Abstract
Peroxynitrite promotes mitochondrial permeability transition-dependent rapid u937 cell necrosis: survivors proliferate with kinetics superimposable on those of untreated cells: P. Sestili, et al.; Free Radic Res. 34, 513 (2001) Abstract
Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention: L. Virag, et al.; Toxicol. Lett. 140-141, 113 (2003), (Review) Abstract
Preventing nitrite contamination in tetramethylammonium peroxynitrite solutions: P. Latal, et al.; Inorg. Chem. 43, 6519 (2004) Abstract
Further Categories Containing This Product:
DNA Repair Other ProductsPARP Other Products
 
 

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