ALEXIS Biochemicals: Phalloidin

ALX-350-265

Revised 17-Dec-07

Phalloidin
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products for Cytoskeletal Research

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-265-M001		1 mg	135.00 USD

Product Specification

FORMULA:	C₃₅H₄₈N₈O₁₁S
MW:	788.9
CAS NUMBER:	17466-45-4
MERCK INDEX:	14: 7196
SOURCE/HOST:	Isolated from Amanita phalloides mushrooms.
PURITY:	≥95%
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in DMSO, dimethyl formamide, methanol, 100% ethanol or water (warm).
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	VERY TOXIC.

Product Description

Binds to polymeric actin with high affinity. Stabilizes filaments and decreases concentration of monomeric actin.

Product Specific Literature References

Interaction of phalloidin with actin: A.M. Lengsfeld, et al.; PNAS 71, 2803 (1974) Abstract
Interaction of actin with phalloidin: polymerization and stabilization of F-actin: P. Dancker, et al.; Biochim. Biophys. Acta 400, 407 (1975) Abstract
Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth: J. Wehland, et al.; PNAS 74, 5613 (1977) Abstract
What we have learned from phalloidin: M. Frimmer; Toxicol Lett. 35, 169 (1987) Abstract
Effects of cytochalasin and phalloidin on actin: J.A. Cooper; J. Cell. Biol. 105, 1473 (1987), (Review) Abstract
Position and orientation of phalloidin in F-actin determined by X-ray fiber diffraction analysis: T. Oda, et al.; Biophys. J. 88, 2727 (2005) Abstract

Further Categories Containing This Product:

Amanitins & Phalloidins / Related Products • Actin / Related Products

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