ALEXIS Biochemicals: Phorbol 12,13-didecanoate

ALX-445-002

Revised 03-Dec-07

Phorbol 12,13-didecanoate
SYNONYMS	PDD
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Phorbols / Phorbol Esters

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-445-002-M001		1 mg	20.00 USD
ALX-445-002-M005		5 mg	65.00 USD

Product Specification

FORMULA:	C₄₀H₆₄O₈
MW:	672.9
CAS NUMBER:	24928-17-4
RTECS:	GZ0653000
PURITY:	≥99% (HPLC)
FORMULATION:	Lyophilized.
SOLUBILITY:	Soluble in DMSO or 100% ethanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.
HAZARD:	MAY BE CARCINOGENIC. HIGHLY IRRITANT. VERY TOXIC.

Product Description

Very potent and hydrophobic protein kinase C (PKC) activator.

Product Specific Literature References

Altered growth properties of normal human cells induced by phorbol 12,13-didecanoate: R. W. Trewyn & H. B. Gatz; In Vitro 20, 409 (1984) Abstract
Inhibition of queuine uptake in diploid human fibroblasts by phorbol-12,13-didecanoate. Requirement for a factor derived from early passage cells:: M. S. Elliott & J. R. Katze; J. Biol. Chem. 261, 13019 (1986) Abstract
Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay: L. Saraiva, et al.; Eur. J. Pharmacol. 491, 101 (2004) Abstract

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