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ALX-210-911 Revised 02-May-05
Polyclonal Antibody to NM23-H1 (K73)
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SYNONYMS anti-GAAD PAb (K73)
anti-Granzyme A-activated DNase PAb (K73)
PRODUCT LINE Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY Granzymes Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-911-C100   100 µg 350.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Protein A-affinity purified.
FORMULATION: Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN: Recombinant human NM23-H1.
SPECIFICITY: Recognizes human and mouse NM23-H1 and NM23-H2.
CROSSREACTIVITY PROTEINS: NM23-H2.
APPLICATION: Immunocytochemistry (1:100)
Immunohistochemistry (paraffin sections (1:200))
Western Blot (1:100-1:500).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored at -20°C.
HANDLING: Avoid freeze/thaw cycles.
Product Images
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Product Specific Literature References
Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis: A. D'Angelo, et al.; Cancer Cell 5, 137 (2004) Abstract
Overexpression of h-prune in breast cancer is correlated with advanced disease status: M. Zollo, et al.; Clin. Cancer Res. 11, 199 (2005) Abstract
General Information
MANUFACTURER Manufactured by Apotech Corporation.
General Literature References
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor: Z. Fan, et al.; Cell 112, 659 (2003) Abstract
The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal: J. Lieberman; Nat. Rev. Immunol. 3, 361 (2003) Abstract
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity: A. Forus, et al.; Oncogene 20, 6881 (2001) Abstract
Evidence for interaction between human PRUNE and nm23-H1 NDPKinase: A. Reymond, et al.; Oncogene 18, 7244 (1999) Abstract
Further Categories Containing This Product:
Polyclonal Antibodies • Tumor Suppressors/Related Products
 
 
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