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ALX-210-840 Revised 08-Oct-07
Polyclonal Antibody to CCR10 (human)
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SYNONYMS anti-C-C Chemokine Receptor 10 (human) PAb
anti-G-Protein Coupled Receptor 2 (human) PAb
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY CC Chemokines & Receptors / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-840-C100   100 µg 267.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Protein G-affinity purified.
FORMULATION: Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to C-terminal aa 350-362 (S350APTETHSLSWDN362) of human CCR10 (C-C chemokine receptor 10; G-protein coupled receptor 2). This sequence is completely conserved in mouse CCR10.
SPECIFICITY: Recognizes human CCR10. Detects a band of ~40kDa by Western blot.
APPLICATION: Flow Cytometry (see [2])
Immunohistochemistry (see [1])
Western Blot (1-2µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
Product Images
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Product Specific Literature References
[1] Expression of the T-helper 2-specific chemokine receptor CCR4 on CCR10-positive lymphocytes in atopic dermatitis skin but not in psoriasis skin: C. Vestergaard, et al.; Br. J. Dermatol. 149, 457 (2003) Abstract
[2] Nickel-responding T cells are CD4+ CLA+ CD45RO+ and express chemokine receptors CXCR3, CCR4 and CCR10: H. Moed, et al.; Br. J. Dermatol. 151, 32 (2004) Abstract
[3] Monocyte chemotactic protein-1 is a potential player in the negative cross-talk between adipose tissue and skeletal muscle: H. Sell, et al.; Endocrinology 147, 2458 (2006) Abstract; Full Text
[4] In vitro and in vivo studies on CCR10 regulation by Annexin A1: F.C. Rodrigues-Lisoni, et al.; FEBS Lett. 580, 1431 (2006) Abstract
General Literature References
Cloning, expression, and chromosomal mapping of a novel human CC- chemokine receptor (CCR10) that displays high-affinity binding for MCP-1 and MCP-3  : J.A. Bonini, et al.; DNA Cell Biol. 16, 1249 (1997) Abstract
Cloning and characterization of a novel promiscuous human beta-chemokine receptor D6  : R.J. Nibbs, et al.; J. Biol. Chem. 272, 32078 (1997) Abstract; Full Text
Identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK  : J. Gosling, et al.; J. Immunol. 164, 2851 (2000) Abstract
Identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine  : D.I. Jarmin, et al.; J. Immunol. 164, 3460 (2000) Abstract
International union of pharmacology. XXII. Nomenclature for chemokine receptors  : P.M. Murphy, et al.; Pharmacol. Rev. 52, 145 (2000), (Review) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 

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