ALEXIS Biochemicals: Polyclonal Antibody to CREB Binding Protein

ALX-210-229

Revised 23-Feb-05

Polyclonal Antibody to CREB Binding Protein
SYNONYMS	anti-CBP PAb
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	CREB & CREB Binding Protein/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-229-C100		100 µg	379.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
SOURCE/HOST:	From rabbit.
CONCENTRATION:	1mg/ml.
FORMULATION:	Liquid. Epitope-affinity purified IgG in PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:	Synthetic peptide corresponding to aa 162-176 (A¹⁶²TSSPATSQTGPGIC¹⁷⁶) in the nuclear factor binding domain of human CBP (CREB binding protein).
SPECIFICITY:	Recognizes human and mouse CBP. Detects a band of ~265kDa by Western blot.
APPLICATION:	Western Blot (1-2µg/ml)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:	For Blocking Peptide see Prod. No. ALX-153-023.

General Information

CREB binding protein (CBP) is a transcriptional coactivator closely related to p300, interacting with many different DNA-binding transcription factors including nuclear hormone receptors, CREB (cyclic AMP-responsive enhancer binding protein), cFos, c-Jun/v-Jun, c-Myb/v-Myb, TFIIB, and MyoD. CBP displays histone acetyltransferase (HAT) activity, capable of acetylating all four core histone particles in nucleosomes.