ALEXIS Biochemicals: Polyclonal Antibody to Dopamine-β-hydroxylase

ALX-210-560

Revised 29-Nov-04

Polyclonal Antibody to Dopamine-β-hydroxylase
SYNONYMS	anti-DBH PAb
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	Dopaminergics & Dopamine Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-560-R250		250 µl	320.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Rat
SOURCE/HOST:	From sheep.
FORMULATION:	Liquid. Neat serum containing 0.2% sodium azide.
IMMUNOGEN:	Synthetic peptide corresponding to aa 43-62 (S⁴³EPPESPFPY HIPLDPEGTL⁶²) of N-terminal rat DBH (dopamine-β-hydroxylase). This sequence is highly conserved (>85% homology) in human, bovine and mouse DBH.
SPECIFICITY:	Recognizes rat DBH. Specifically stains chromaffin cells of the adrenal medulla and DBH-containing cells of the sympathetic nervous system, including locus coeruleus and medulla oblongata. Cross-reactivity with other species has not been tested, but broad species cross-reactivity is expected due to conservation of the immunogenic sequence.
APPLICATION:	Immunocytochemistry (1:5'000-1:10'000) Immunohistochemistry (frozen sections (1:20'000-1:50'000)) Western Blot (1:5'000-1:10'000 by ECL detection) Optimal conditions must be determined individually for each application.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:	Avoid freeze/thaw cycles.

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General Information

Dopamine-β-hydroxylase (DBH) is the enzyme responsible for conversion of dopamine to noradrenaline. Tissue specificity consists of chromaffin granules of the adrenal medulla and synaptic vesicles of the sympathetic nervous system. It exists as both, a soluble and membrane-bound form in chromaffin granules.

Further Categories Containing This Product:

Adrenergics & Adrenergic Receptors / Related Products • Polyclonal Antibodies

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