ALEXIS Biochemicals: Polyclonal Antibody to (E)-4-Hydroxynonenal

ALX-210-767

Revised 30-Sep-08

Polyclonal Antibody to (E)-4-Hydroxynonenal
SYNONYMS	anti-HNE PAb
PRODUCT LINE	Oxidative Stress
PRODUCT CATEGORY	Oxidative Stress Markers & Reagents / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-767-R100		100 µl	495.00 USD

Product Specification

SOURCE/HOST:	From rabbit.
FORMULATION:	Lyophilized. Neat serum containing 0.05% sodium azide.
RECONSTITUTION:	Reconstitute with 100µl PBS.
IMMUNOGEN:	Free recombinant HNE (E)-4-hydroxynonenal.
SPECIFICITY:	Recognizes HNE-adducts.
APPLICATION:	ELISA (1:1'000-1:10'000) Immunohistochemistry (1:500-1:1'000) Western Blot (1:500-1:1'000)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Product Specific Literature References

Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes: K. Uchida, et al.; PNAS 90, 8742 (1993) Abstract
Formation of 8-hydroxy-2'-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in human renal-cell carcinoma: K. Okamoto, et al.; Int. J. Cancer 58, 825 (1994) Abstract
Immunocytochemical detection of lipid peroxidation in phagosomes of human neutrophils: correlation with expression of flavocytochrome b: M.T. Quinn, et al.; J. Leukoc. Biol. 57, 415 (1995) Abstract
Characterization of epitopes recognized by 4-hydroxy-2-nonenal specific antibodies: K. Uchida, et al.; Arch. Biochem. Biophys. 324, 241 (1995) Abstract
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease: A. Yoritaka, et al.; PNAS 93, 2696 (1996) Abstract
alpha-Phenyl-n-tert-butyl-nitrone attenuates hypoxic-ischemic white matter injury in the neonatal rat brain: S. Lin, et al.; Brain Res. 1007, 132 (2004) Abstract
Acquired Resistance to Acetaminophen Hepatotoxicity is Associated with Induction of Multidrug Resistance-Associated Protein 4 (Mrp4) in Proliferating Hepatocytes: L.M. Aleksunes, et al.; Toxicol. Sci. 104, 261 (2008) Abstract
Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes: K. Stadler, et al.; Free Radic. Biol. Med. Epub ahead of print, (2008) Abstract