ALEXIS Biochemicals: Polyclonal Antibody to GITRL (mouse)

ALX-210-375

Revised 30-Oct-06

Polyclonal Antibody to GITRL (mouse)
SYNONYMS	anti-TNFSF 18 (mouse) PAb anti-Glucocorticoid-induced TNF Receptor Ligand (mouse) PAb
PRODUCT LINE	Chemokines & Cytokines
PRODUCT CATEGORY	GITR & GITRL Antibodies

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-375-C100		100 µg	290.00 USD
ALX-210-375B-C050	Biotin	50 µg	290.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Mouse
SOURCE/HOST:	From rabbit.
CONCENTRATION:	1mg/ml.
FORMULATION:	Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN:	Recombinant mouse GITRL.
SPECIFICITY:	Recognizes both natural and recombinant mouse GITRL. Does not cross-react with human GITRL (AITRL).
APPLICATION:	ELISA (direct and indirect: 1:5’000-1:10’000) Flow Cytometry (1:1’000) Western Blot (1:2’000-1:5’000 using ECL; suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5 % skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.

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Product Specific Literature References

Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells: K.Y. Yu, et al.; BBRC 310, 433 (2003) Abstract
The soluble glucocorticoid-induced tumor necrosis factor receptor causes cell cycle arrest and apoptosis in murine macrophages: H.H. Shin, et al.; BBRC 316, 24 (2004) Abstract
Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells: H.H. Shin, et al.; Bone 36, 832 (2005) Abstract

General Information

MANUFACTURER

Manufactured by AdipoGen, Inc.

Further Categories Containing This Product:

Polyclonal Antibodies

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