ALEXIS Biochemicals: Polyclonal Antibody to HERG3

ALX-215-053

Revised 01-Jun-07

Polyclonal Antibody to HERG3
SYNONYMS	anti-Erg3 PAb anti-Ether-a-go-go Related Protein 3 PAb anti-KCNH7 PAb anti-Voltage-gated Potassium Channel Subfamily H Member 7 PAb anti-Voltage-gated Potassium Channel Kv11.3 PAb
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	K+ Channel Antibodies

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-215-053-R100		100 µl	270.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
SOURCE/HOST:	From rabbit.
PURITY DETAIL:	Protein A-affinity purified.
FORMULATION:	Liquid. In 100mM TRIS containing 100mM glycine.
IMMUNOGEN:	Recombinant HERG3 (human ether-a-go-go related protein 3) (aa 1115-1194).
SPECIFICITY:	Recognizes HERG3 and mouse Erg3.
APPLICATION:	Immunocytochemistry (1:50-1:200) Immunohistochemistry (frozen sections, paraffin sections) (1:100-1:400)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	-20°C
LONG TERM STORAGE:	-80°C
HANDLING:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.

Product Specific Literature References

Interneurons transiently express the ERG K+ channels during development of mouse spinal networks in vitro: F. Furlan, et al.; Neuroscience 135, 1179 (2005) Abstract
Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: evidence for coassembly of different subunits: L. Guasti, et al.; J. Comp. Neurol. 491, 157 (2005) Abstract

General Information

The ether-a-go-go related gene family of K⁺ channels (HERG/Erg) comprises three members, HERG1/Erg1, HERG2/Erg2, HERG3/Erg3. HERG channel activity is relevant to tumor cell biology. It controls cell proliferation, especially in leukaemias. HERG channels are thus considered novel diagnostic and prognostic factors in human cancers, as well as targets for anti-neoplastic therapies.

Further Categories Containing This Product:

Cancer Other Products • Polyclonal Antibodies

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