ALEXIS Biochemicals: Polyclonal Antibody to HIF-1α

ALX-210-069

Revised 16-Jul-08

Polyclonal Antibody to HIF-1α
SYNONYMS	anti-Hypoxia-inducible Factor 1α PAb anti-ARNT-interacting Protein PAb
PRODUCT LINE	Oxidative Stress
PRODUCT CATEGORY	Hypoxia-inducible Factor [HIF] / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-069-C050		50 µg	220.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
SOURCE/HOST:	From rabbit.
CONCENTRATION:	2.8mg/ml
PURITY DETAIL:	Protein G-affinity purified.
FORMULATION:	Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
IMMUNOGEN:	Recombinant HIF-1α (hypoxia-inducible factor-1a) (aa 609-826).
SPECIFICITY:	Recognizes human and mouse HIF-1α.
APPLICATION:	Immunohistochemistry (1:200) Immunoprecipitation (1-5µg) Western Blot (1µg/ml)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis: N. Tang, et al.; Cancer Cell 6, 485 (2004) Abstract
Epidermal sensing of oxygen is essential for systemic hypoxic response: A.T. Boutin, et al.; Cell 133, 206 (2008) Abstract
Critical Role of HIF-1alpha in Keratinocyte Defense against Bacterial Infection: C. Peyssonnaux, et al.; J. Invest. Dermatol. 128, 1964 (2008) Abstract

General Literature References

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin: C. C. Hudson, et al.; Mol. Cell Biol. 22, 7004 (2002) Abstract; Full Text

Further Categories Containing This Product:

Aryl Hydrocarbon Receptor / Related Products • Polyclonal Antibodies

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