ALEXIS Biochemicals: Polyclonal Antibody to PARP-1

ALX-210-302

Revised 12-Mar-07

Polyclonal Antibody to PARP-1
SYNONYMS	anti-Poly(ADP-ribose) Polymerase-1 PAb
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	PARP-1

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-302-R100		100 µl	235.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse Others
SOURCE/HOST:	From rabbit.
FORMULATION:	Liquid. Neat serum containing 0.1% sodium azide.
IMMUNOGEN:	Recombinant human PARP-1 (poly(ADP-ribose) polymerase-1) (aa 1-1014).
SPECIFICITY:	Recognizes human, mouse, bovine, chicken and xenopus PARP-1. Detects bands of ~116kDa (PARP-1) and ~85kDa (apoptosis-induced cleavage fragment) by Western blot. Does not cross-react with PARP-2.
APPLICATION:	ELISA Immunocytochemistry (1:4'000) Immunohistochemistry (frozen sections, paraffin sections) Immunoprecipitation (1:400) Western Blot (1:4'000)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C
USE/STABILITY:	Stable for at least one year when stored at +4°C.
HANDLING:	Avoid freeze/thaw cycles.

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Product Specific Literature References

Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas- mediated apoptotic pathways: L. Dubrez, et al.; EMBO J. 15, 5504 (1996) Abstract
Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells: B. Bellosillo, et al.; Blood 89, 3378 (1997) Abstract; Full Text
Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication: F. Dantzer, et al.; Nucl. Acids Res. 26, 1891 (1998) Abstract; Full Text

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Polyclonal Antibodies

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