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ALX-210-771 Revised 07-Dec-06
Polyclonal Antibody to PARP-1 (1-232) (human)
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SYNONYMS anti-Poly(ADP-ribose) Polymerase-1 (1-232) (human) PAb
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY PARP-1
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-771-1   1 Vial 220.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
SOURCE/HOST: From rabbit.
FORMULATION: Lyophilized.
RECONSTITUTION: Reconstitute with 100µl of sterile, distilled water containing 0.02 % sodium azide (optional).
IMMUNOGEN: Recombinant human PARP-1 (poly(ADP-ribose) polymerase-1) DNA-binding domain (aa 1-232).
SPECIFICITY: Recognizes human PARP-1. Detects bands of ~116kDa (full length PARP-1) and ~29kDa (apoptosis-induced cleavage fragment) by Western blot. Does not cross-react with PARP-2.
APPLICATION: ELISA
Immunocytochemistry
Immunoprecipitation
Western Blot (1:1'000)
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: +4°C
HANDLING: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
Product Specific Literature References
NAD+ analogs substituted in the purine base as substrates for poly(ADP- ribosyl) transferase: S.L. Oei, et al.; FEBS Lett. 397, 17 (1996) Abstract
Protein-protein interaction of the human poly(ADP-ribosyl)transferase depends on the functional state of the enzyme: J. Griesenbeck, et al.; Biochemistry 36, 7297 (1997) Abstract
The role of poly(ADP-ribosyl)ation: S.L. Oei, et al.; Rev. Physiol. Biochem. Pharmacol. 131, 127 (1997), (Review) Abstract
Interaction of the transcription factor YY1 with human poly(ADP- ribosyl) transferase: S.L. Oei, et al.; BBRC 240, 108 (1997) Abstract
The role of poly(ADP-ribosyl)ation: S.L. Oei, et al.; Rev. Physiol. Biochem. Pharmacol. 131, 127 (1997), (Review) Abstract
A novel function of poly(ADP-ribosyl)ation: silencing of RNA polymerase II-dependent transcription: S.L. Oei, et al.; Biochemistry 37, 1465 (1998) Abstract
Further Categories Containing This Product:
Apoptosis & Necrosis Detection Other Products • Polyclonal Antibodies
 
 
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