ALEXIS Biochemicals: Polyclonal Antibody to PARP-1 (215-228)

ALX-210-220

Revised 07-Dec-06

Polyclonal Antibody to PARP-1 (215-228)
SYNONYMS	anti-Poly(ADP-ribose) Polymerase-1 (215-228) PAb
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	PARP-1

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-220-R100		100 µl	240.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Others
SOURCE/HOST:	From rabbit.
FORMULATION:	Liquid. Contains 0.02% sodium azide.
IMMUNOGEN:	Synthetic peptide corresponding to aa 215-228 (G²¹⁵VDEVAKKKSKKEK²²⁸) of human PARP-1 (poly(ADP-ribose) polymerase-1).
SPECIFICITY:	Recognizes human, bovine and chicken PARP-1. Detects bands of ~116kDa (full-length PARP-1) and ~85kDa (apoptosis-induced cleavage fragment) by Western blot.
APPLICATION:	ELISA (1:210’000) Immunocytochemistry (1:50) Western Blot (1:2'000-1:5'000) Optimal conditions must be determined individually for each application.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C

Product Specific Literature References

Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study: D. Lamarre, et al.; Biochim. Biophys. Acta 950, 147 (1988) Abstract

General Information

During apoptosis PARP-1 is cleaved between Asp²¹⁴ and Gly²¹⁵ to yield two fragments of 29kDa and 85kDa. This cleavage site is conserved in human, bovine and chicken PARP-1.

Further Categories Containing This Product:

Polyclonal Antibodies

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