ALEXIS Biochemicals: Polyclonal Antibody to Pannexin-1 (human) (AT124)

ALX-210-949

Revised 29-Oct-07

Polyclonal Antibody to Pannexin-1 (human) (AT124)
SYNONYMS	anti-Pannexin-1 (human) PAb (AT124)
PRODUCT LINE	Inflammation
PRODUCT CATEGORY	Inflammasome

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-949-C100		100 µg	350.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
SOURCE/HOST:	From rabbit.
CONCENTRATION:	1mg/ml
PURITY DETAIL:	Epitope-affinity purified.
FORMULATION:	Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:	Synthetic peptide corresponding to 15 aa near the C-terminus of human pannexin-1.
SPECIFICITY:	Recognizes human pannexin-1.
APPLICATION:	Western Blot (1:1’000)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

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General Information

Pannexin-1 belongs to a new family of membrane proteins with homology to invertebrate gap junction proteins innexins. Pannexin-1 has recently been involved in the NALP (inflammasome)-mediated caspase-1 activation and IL-1β secretion.
MANUFACTURER	Manufactured by Apotech Corporation.

General Literature References

Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling: T.D. Kanneganti, et al.; Immunity 26, 433 (2007) Abstract

Further Categories Containing This Product:

Polyclonal Antibodies

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