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ALX-210-205 Revised 15-May-07
Polyclonal Antibody to Peroxisomal Membrane Protein 70 (mouse)
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SYNONYMS anti-PMP70 (mouse) PAb
anti-ABCD3 (mouse) PAb
PRODUCT LINE Oxidative Stress
PRODUCT CATEGORY Cell Stress, Oxidative Stress & Redox Signalling Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-205-C100   100 µg 379.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Epitope-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 644-659 (CN644YEFKKITED TVEFGS659) of C-terminal rat PMP70 (peroxisomal membrane protein 70). This sequence is completely conserved in mouse PMP70 and differs from human PMP70 by a single aa substitution.
SPECIFICITY: Recognizes mouse PMP70. Detects a band of ~70kDa by Western blot.
APPLICATION: Flow Cytometry
Western Blot (1:500)
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles.
BLOCKING PEPTIDE: For Blocking Peptide see Prod. No. ALX-165-036.
General Information
Peroxisomes are single membrane organelles which are involved in many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via β-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum’s disease. Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal β-oxidation enzymes.
Further Categories Containing This Product:
Polyclonal Antibodies
 
 

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