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ALX-210-467 Revised 30-Jul-07
Polyclonal Antibody to RELM-β (mouse)
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SYNONYMS anti-Resistin-like Molecule-β (mouse) PAb
anti-FIZZ2 (mouse) PAb
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Resistin & Resistin-like Molecules [RELMs]/Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-467-C100   100 µg 310.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 1mg/ml.
PURITY DETAIL: Purified IgG.
FORMULATION: Liquid. In PBS, pH 7.4. Contains no preservatives.
IMMUNOGEN: Recombinant mouse RELM-β (resistin-like molecule-β).
SPECIFICITY: Recognizes mouse RELM-β. Does not cross-react with human RELM-β.
APPLICATION: ELISA (direct and indirect: 1:5’000-1:10’000)
Western Blot (1:5’000-1:10’000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Product Images
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General Information
RELM-β (resistin-like molecule-β; FIZZ2) is a 19 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELM-β, and its molecular targets, are not fully known, but it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver [1]. Interestingly, the molecular structure of RELM-β is highly homologous to that of the adipose-derived cytokine resistin.
MANUFACTURER Manufactured by AdipoGen, Inc.
General Literature References
[1] Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production  : M.W. Rajala, et al. ; J. Clin. Invest. 111, 225 (2003) Abstract; Full Text
Further Categories Containing This Product:
Polyclonal Antibodies
 
 

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