ALEXIS Biochemicals: Polyclonal Antibody to SorLA (F3)

ALX-215-061

Revised 31-Jul-08

Polyclonal Antibody to SorLA (F3)
SYNONYMS	anti-LR11 PAb (F3) anti-SorL1 PAb (F3) anti-Sorting Protein-related Receptor Containing LDLR Class A Repeats PAb (F3) anti-Low-density Lipoprotein Receptor Relative with 11 Ligand-binding Repeats PAb (F3)
PRODUCT LINE	Neurobiology
PRODUCT CATEGORY	Neuropeptides & Receptors Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-215-061-1		1 Vial	250.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse Rat
SOURCE/HOST:	From rabbit.
FORMULATION:	Lyophilized.
RECONSTITUTION:	Reconstitute with 50μl distilled water.
IMMUNOGEN:	Recombinant mouse SorLA (aa 1384-1676 representing the first 4.5 extracellular fibronectin type III domain).
SPECIFICITY:	Recognizes human, mouse and rat SorLA.
APPLICATION:	Immunocytochemistry (1:1’000) Western Blot (1:3’000)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C
HANDLING:	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Product Description

Recognizes transmembrane SorLA and also the shed ectodomain.

Product Specific Literature References

Ectodomain shedding, translocation and synthesis of SorLA are stimulated by its ligand head activator: W. Hampe, et al.; J. Cell Sci. 113, 4475 (2000) Abstract; Full Text
Characterization of the VPS10 domain of SorLA/LR11 as binding site for the neuropeptide HA: J. Lintzel, et al.; Biol. Chem. 383, 1727 (2002) Abstract