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ALX-210-368 Revised 30-Oct-07
Polyclonal Antibody to Toll-like Receptor 9
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SYNONYMS anti-TLR9 PAb
anti-CD289 PAb
PRODUCT LINE Inflammation
PRODUCT CATEGORY TLR Antibodies
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-368-C100   100 µg 293.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST: From rabbit.
CONCENTRATION: 0.5mg/ml
PURITY DETAIL: Protein G-affinity purified IgG.
FORMULATION: Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
IMMUNOGEN: Synthetic peptide corresponding to aa 275-291 of mouse TLR9 (Toll-like receptor 9) (extracellular domain).
SPECIFICITY: Recognizes human and mouse TLR9. Detects a band of ~113kDa by Western blot.
APPLICATION: Flow Cytometry (intracellular (1-2µg/106))
Flow Cytometry (cell surface (see [6]))
Immunocytochemistry (see [5])
Immunocytochemistry (paraffin sections (see [8]); frozen sections (10µg/ml) (see [6]))
Western Blot (0.5-1µg/ml)
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 6 months when stored at +4°C.
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Product Specific Literature References
[1] Toll-like receptor 9 regulates tumor necrosis factor-alpha expression by different mechanisms. Implications for osteoclastogenesis: A. Amcheslavsky, et al.; J. Biol. Chem. 279, 54039 (2004) Abstract; Full Text
[2] IFN-gamma overcomes low responsiveness of myeloid dendritic cells to CpG DNA: M. Uchijima, et al.; Immunol. Cell Biol. 83, 92 (2005) Abstract
[3] Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects: I.N. Buhtoiarov, et al.; J. Immunol. 176, 309 (2006) Abstract; Full Text
[4] Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide: L. Chen, et al.; J. Immunol. 177, 2373 (2006) Abstract; Full Text
[5] Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity: M.A. Merrell, et al.; Mol. Cancer Res. 4, 437 (2006) Abstract; Full Text
[6] Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice: P.S. Patole, et al.; Nephrol. Dial. Transplant. 21, 3062 (2006) Abstract
[7] Toll like receptor-9 agonists stimulate prostate cancer invasion in vitro: J.M. Ilvesaro, et al.; Prostate 67, 774 (2007) Abstract
[8] Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation: N. Tran, et al.; ; J. Clin. Endocrinol. Metab. 92, 2773 (2007) Abstract
Further Categories Containing This Product:
Polyclonal Antibodies • CD Antibodies
 
 
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