ALEXIS Biochemicals: Polyclonal Antibody to ZUD (AT116)

ALX-210-939

Revised 11-May-07

Polyclonal Antibody to ZUD (AT116)
SYNONYMS	anti-ZU5 and Death Domain-containing Inhibitor of NF-κB PAb (AT116) anti-Unc-5 Homolog C (C. elegans)-like PAb (AT116) anti-UNC5CL PAb (AT116)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Netrins & Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-939-C100		100 µg	380.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
SOURCE/HOST:	From rabbit.
CONCENTRATION:	1mg/ml
PURITY DETAIL:	Protein A-affinity purified.
FORMULATION:	Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:	Recombinant human ZUD domain (aa 402-518).
SPECIFICITY:	Recognizes human and mouse ZUD.
APPLICATION:	Immunocytochemistry (1:100) Immunoprecipitation (1:200) Western Blot (1:1’000)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.

General Information

ZUD is cytoplasmic protein with a ZU5 and death domain. It interacts with the NF-κB subunit p105 and transactivator p65 and inhibits NF-κB -dependent transcription when its overexpressed. ZUD seems to be a inhibitor of NF-κB signalling, and enhance cell death to apoptotic stimuli like TNF and TRAIL.
MANUFACTURER	Manufactured by Apotech Corporation.

General Literature References

Identification of a ZU5 and death domain-containing inhibitor of NF-kappaB: J. Zhang, et al.; J. Biol. Chem. 279, 17819 (2004) Abstract; Full Text

Further Categories Containing This Product:

TNF & TNF Receptor Superfamily Other Products • TRAIL & TRAIL Receptors Other Products • NF-kB Pathway Inhibitors • Polyclonal Antibodies

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