ALEXIS Biochemicals: Polyclonal Antibody to Estrogen Receptor β

ALX-210-180

Revised 21-Dec-06

Polyclonal Antibody to Estrogen Receptor β
SYNONYMS	anti-ERβ PAb
PRODUCT LINE	DNA Regulation / Transcription
PRODUCT CATEGORY	Estrogen & Estrogen Receptors/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-180-C050		50 µg	379.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Rat
SOURCE/HOST:	From rabbit.
CONCENTRATION:	1mg/ml
PURITY DETAIL:	Epitope-affinity purified IgG.
FORMULATION:	Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
IMMUNOGEN:	Synthetic peptide corresponding to aa 512-530(C⁵¹²SPAEDSKSK EGSQNPQSQ⁵³⁰) of C-terminal human ERβ (estrogen receptor β).
SPECIFICITY:	Recognizes human and rat ERβ. Detects a band of ~55kDa by Western blot. Does not cross-react with ERα.
APPLICATION:	Immunohistochemistry (frozen sections (2-5µg/ml), paraffin sections (2-5µg/ml)) Western Blot (1µg/ml)
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.
BLOCKING PEPTIDE:	For Blocking Peptide see Prod. No. ALX-155-029.

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Product Specific Literature References

Differential Regulation of Estrogen Receptor Subtypes alpha and beta in Human Aortic Smooth Muscle Cells by Oligonucleotides and Estradiol: F. Barchiesi, et al.; J. Clin. Endocrinol. Metab. 89, 2373 (2004) Abstract; Full Text
Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast: R.K. Dubey, et al.; J. Clin. Endocrinol. Metab. 90, 247 (2005) Abstract; Full Text